Protein melan-A also known as melanoma antigen recognized by T cells 1 or MART-1 is a protein that in humans is encoded by the MLANA gene. A fragment of the protein, usually consisting of the nine amino acids 27 to 35, is bound by MHC class I complexes which present it to T cells of the immune system. These complexes can be found on the surface of melanoma cells. Decameric peptides (26-35) are being investigated as cancer vaccines.
CAT | Product Name | Target Species | Antibody Clone | Antibody Host | Receptor Construction | Vector Type | Targeting Cell Type | Inquiry & Datasheet |
CAR-YF005 | Anti-MART-1 (M1) h(4-1BB-CD3ζ) CAR, pCDCAR1 | Human | M1 | Rabbit | scFv-4-1BB-CD3ζ | Lentiviral vector | T cell | |
CAR-YF006 | Anti-MART-1 (M1) h(CD28-CD3ζ) CAR, pCDCAR1 | Human | M1 | Rabbit | scFv-CD28-CD3ζ | Lentiviral vector | T cell | |
CAR-YF007 | Anti-MART-1 (M7) h(4-1BB-CD3ζ) CAR, pCDCAR1 | Human | M7 | Mouse | scFv-4-1BB-CD3ζ | Lentiviral vector | T cell | |
CAR-YF008 | Anti-MART-1 (M7) h(CD28-CD3ζ) CAR, pCDCAR1 | Human | M7 | Mouse | scFv-CD28-CD3ζ | Lentiviral vector | T cell | |
CAR-ZP072 | Anti-MART-1 (ECD) h(41BB-CD3ζ) CAR, pCDCAR1 | Human | ECD | Rat | scFv-4-1BB-CD3ζ | Lentiviral vector | T cell | |
CAR-ZP073 | Anti-MART-1 (ECD) h(CD28-CD3ζ) CAR, pCDCAR1 | Human | ECD | Rat | scFv-CD28-CD3ζ | Lentiviral vector | T cell |
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