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MART-1

Protein melan-A also known as melanoma antigen recognized by T cells 1 or MART-1 is a protein that in humans is encoded by the MLANA gene. A fragment of the protein, usually consisting of the nine amino acids 27 to 35, is bound by MHC class I complexes which present it to T cells of the immune system. These complexes can be found on the surface of melanoma cells. Decameric peptides (26-35) are being investigated as cancer vaccines.

Associated Disease

CAR Vector Products Product list:

Catalog Targeting
Cell Type 		Generation Antibody
Clone 		Vector
Length 		Vector
Type 		Vector Design Antibody
Host 		Data
sheet		 Price
CAR-YF005 T cell Second M1 ~8kb Lentiviral vector scFv-4-1BB-CD3ζ Rabbit Inquiry
CAR-YF006 T cell Second M1 ~8kb Lentiviral vector scFv-CD28-CD3ζ Rabbit Inquiry
CAR-YF007 T cell Second M7 ~8kb Lentiviral vector scFv-4-1BB-CD3ζ Mouse Inquiry
CAR-YF008 T cell Second M7 ~8kb Lentiviral vector scFv-CD28-CD3ζ Mouse Inquiry
CAR-ZP072 T cell Second ECD ~8kb Lentiviral vector scFv-4-1BB-CD3ζ Rat Inquiry
CAR-ZP073 T cell Second ECD ~8kb Lentiviral vector scFv-CD28-CD3ζ Rat Inquiry

TCR Vector Products Product list:

Catalog Target Target
Species 		Antibody
Clone 		scFv-Host
Animal 		Vector
length 		Vector
Type 		Epitope Format HLA Data
sheet		 Price
TCR-C132Z MART-1 Human DMF4 Human ~8kb Lentiviral AAGIGILTV Non-modified HLA-A2 Inquiry
TCR-C133Z MART-1 Human DMF5 Human ~8kb Lentiviral AAGIGILTV Non-modified HLA-A2 Inquiry
TCR-C134Z MART-1 Human JKF6 Human ~8kb Lentiviral ALGIGILTV Non-modified HLA-A2 Inquiry
TCR-C135Z MART-1 Human DMF5(alpha-D26Y,beta-L98W) Human ~8kb Lentiviral ELAGIGILTV Affinity enhanced HLA-A2 Inquiry
TCR-C136Z MART-1 Human RD1-MART1 High Murinized ~8kb Lentiviral ELAGIGILTV Murinized HLA-A2 Inquiry
TCR-C137Z MART-1 Human F5 Human ~8kb Lentiviral EAAGIGILTV Non-modified HLA-A*0201 Inquiry
TCR-C138Z MART-1 Human 1D3HMCys Murinized ~8kb Lentiviral EAAGIGILTV Murinized and Codon-optimized and Cysteine-modified HLA-A*0201 Inquiry
TCR-C139Z MART-1 Human SIG35α Human ~8kb Lentiviral AAGIGILTV Codon optimized HLA-A2 Inquiry
TCR-C140Z MART-1 Human 5 Human ~8kb Lentiviral EAAGIGILTV Non-modified HLA-A2 Inquiry
TCR-C141Z MART-1 Human 1D3 Human ~8kb Lentiviral EAAGIGILTV Codon optimized HLA-A*0201 Inquiry
TCR-C142Z MART-1 Human DMF4 Human ~8kb Lentiviral EAAGIGILTV Codon optimized HLA-A*0201 Inquiry
TCR-C143Z MART-1 Human 2C2 Human ~8kb Lentiviral EAAGIGILTV Codon optimized HLA-A*0201 Inquiry
TCR-C144Z MART-1 Human MEL5 Human ~8kb Lentiviral AAGIGILTV Non-modified HLA-A*0201 Inquiry
TCR-C145Z MART-1 Human α24β17 Human ~8kb Lentiviral ELAGIGILTV Affinity enhanced HLA-A2 Inquiry
TCR-L064Z MART-1 Human Human 8kb Lentiviral AAGIGILTV Non-modified HLA-A2 Inquiry
TCR-L065 MART-1 Human Human 6000bp retroviral vector AAGIGILTV Non-modified TCR HLA-A2 Inquiry
TCR-L065Z MART-1 Human Human 8kb Lentiviral ELAGIGILTV Non-modified HLA-A2 Inquiry
TCR-L066 MART-1 Human Human 6700-8070bp retroviral vector ELAGIGILTV Non-modified TCR HLA-A2 Inquiry
TCR-L066Z MART-1 Human Murinized (from Human) 8kb Lentiviral ELAGIGILTV Murinized HLA-A2 Inquiry
TCR-L067 MART-1 Human Murinized (from Human) 6700-8070bp retroviral vector ELAGIGILTV Murinized TCR HLA-A2 Inquiry
TCR-L067Z MART-1 Human Murinized (from Human) 8kb Lentiviral ELAGIGILTV Murinized and Cysteine-modified HLA-A2 Inquiry
TCR-L068 MART-1 Human Murinized (from Human) 6700-8070bp retroviral vector ELAGIGILTV Murinized and Cysteine-modified TCR HLA-A2 Inquiry
TCR-L127 MART-1 Human S5-4 Human ~8kb Lentiviral ELAGIGILTV Non-modified HLA-A2 Inquiry
TCR-L128 MART-1 Human DMF5 Human ~8kb Lentiviral ELAGIGILTV Soluble T-cell receptor HLA-A2 Inquiry

TCR Viral Particles Product list:

Catalog Target
Species 		Antibody
Clone 		scFv-Host
Animal 		Packaging
System 		Epitope Format Titer Data
sheet		 Price
VP-TCR-C283 Human DMF4 Human Lentivirus AAGIGILTV Non-modified TCR > 10⁷ IFU/ml Inquiry
VP-TCR-C284 Human DMF5 Human Lentivirus AAGIGILTV Non-modified TCR > 10⁷ IFU/ml Inquiry
VP-TCR-C285 Human JKF6 Human Lentivirus ALGIGILTV Non-modified TCR > 10⁷ IFU/ml Inquiry
VP-TCR-C286 Human DMF5(alpha-D26Y,beta-L98W) Human Lentivirus ELAGIGILTV Affinity enhanced TCR > 10⁷ IFU/ml Inquiry
VP-TCR-C287 Human RD1-MART-1 High Murinized Lentivirus ELAGIGILTV Murinized TCR > 10⁷ IFU/ml Inquiry
VP-TCR-C288 Human F5 Human Lentivirus EAAGIGILTV Non-modified TCR > 10⁷ IFU/ml Inquiry
VP-TCR-C289 Human 1D3HMCys Murinized Lentivirus EAAGIGILTV Murinized and Codon-optimized and Cysteine-modified TCR > 10⁷ IFU/ml Inquiry
VP-TCR-C290 Human SIG35α Human Lentivirus AAGIGILTV Codon optimized TCR > 10⁷ IFU/ml Inquiry
VP-TCR-C291 Human 5 Human Lentivirus EAAGIGILTV Non-modified TCR > 10⁷ IFU/ml Inquiry
VP-TCR-C292 Human 1D3 Human Lentivirus EAAGIGILTV Codon optimized TCR > 10⁷ IFU/ml Inquiry
VP-TCR-C293 Human DMF4 Human Lentivirus EAAGIGILTV Codon optimized TCR > 10⁷ IFU/ml Inquiry
VP-TCR-C294 Human 2C2 Human Lentivirus EAAGIGILTV Codon optimized TCR > 10⁷ IFU/ml Inquiry
VP-TCR-C295 Human MEL5 Human Lentivirus AAGIGILTV Non-modified TCR > 10⁷ IFU/ml Inquiry
VP-TCR-C296 Human α24β17 Human Lentivirus ELAGIGILTV Affinity enhanced TCR > 10⁷ IFU/ml Inquiry
VP-TCR-C297 Human S5-4 Human Lentivirus ELAGIGILTV Non-modified TCR > 10⁷ IFU/ml Inquiry
VP-TCR-C298 Human DMF5 Human Lentivirus ELAGIGILTV Soluble T-cell receptor > 10⁷ IFU/ml Inquiry
VP-TCR-C304 Human Human Lentivirus ELAGIGILTV Non-modified TCR > 10⁷ IFU/ml Inquiry
VP-TCR-C305 Human Murinized (from Human) Lentivirus ELAGIGILTV Murinized and Cysteine-modified TCR > 10⁷ IFU/ml Inquiry
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