Anti-MLANA (ELAGIGILTV) TCR, pMSGV1(TCR-L067)
The vector of anti-MART-1 T cell receptor (TCR) is constructed for the engineering of T cell to target Human MART-1. The T cells are genetically modified through transduction with a retroviral vector expressing MART-1-specific T cell receptor. And the vector product was designed for the treatment of Melanoma.
Details
Targeting Diseases
Melanoma
Vector Length
6700-8070bp
Vector Type
retroviral vector
Antibody Host
Murinized (from Human)
Target
Synonyms
DMF5; MLANA; MART1; MART-1; metastatic melanoma; scFv; FcεRIγ; Chimeric antigen receptor; T cell; Retrovirus; CARs; Lentivirus; chimeric T cell receptors; chimeric immunoreceptors; chimeric antigen receptors; Melan-A
Introduction
Involved in melanosome biogenesis by ensuring the stability of GPR143. Plays a vital role in the
expression, stability, trafficking, and processing of melanocyte protein PMEL, which is critical to the
formation of stage II melanosomes.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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Carcinoma
Datasheet
