MetaVital™ Mouse Glutathione S Transferase Alpha 1 (GSTa1) ELISA Kit

CAT#: ITS-0326-WB32
Product Type: ELISA Kit
Species: Mouse
Target: Mouse Glutathione S Transferase Alpha 1 (GSTa1) protein
Brand: MetaVital™
Development Stage: ADME
ADME Research Domain: Metabolism
Short Description
Quantitatively detects mouse GSTa1 protein levels in biological samples for detoxification and oxidative stress research.
Brand
MetaVital™
Development Stage
ADME
ADME Research Domain
Metabolism
Description
MetaVital™ Mouse Glutathione S Transferase Alpha 1 (GSTa1) ELISA Kit provides a sensitive and reliable platform for measuring GSTa1 concentrations in mouse serum, plasma, tissue homogenates, and cell lysates. This assay supports studies of xenobiotic metabolism, oxidative stress responses, and detoxification pathways in pharmacological and toxicological research.
Features
Highly specific antibody pair enables selective detection of mouse GSTa1 while minimizing interference from other glutathione S-transferase family members.
Sensitive colorimetric ELISA format allows accurate quantification of GSTa1 protein across a broad dynamic concentration range.
Comprehensive kit components including pre-coated plates, standards, detection reagents, and buffers ensure convenient and reproducible experimental workflows.
Optimized assay protocol supports efficient high-throughput analysis while maintaining consistent signal intensity and strong analytical reliability.
Process Relevance
Enables monitoring of GSTa1 expression to assess detoxification capacity and oxidative stress responses in mouse experimental systems.
Application Stage
Drug discovery, preclinical toxicology, biomarker identification, and metabolic pathway research.
Applications
Quantitative ELISA detection of GSTa1 in mouse serum, plasma, tissue homogenates, and cell lysates to investigate detoxification mechanisms, oxidative stress responses, ADME profiling, and drug metabolism.
Qualified With
Internal performance validation using reference standards under defined assay conditions.
Target
Mouse Glutathione S Transferase Alpha 1 (GSTa1) protein
Detection Method
Colorimetric
Sample Type
Serum, plasma and other biological fluids.
Assay Measures
Quantitative
Research Areas
Drug metabolism, pharmacokinetics (ADME), toxicology, oxidative stress biology, pharmacology, enzymology, biomarker discovery, etc.
Size
96 tests
Data Output Type
Quantitative protein concentration measurement using a colorimetric endpoint ELISA assay.
Assay Range
15.6 pg/ml - 1000 pg/ml
LOD
9.38 pg/ml
Species
Mouse
Assay Measures
Quantitative
Storage
Upon receipt, store the kit in accordance with the storage conditions specified in the product manual.
Storage Comment
Avoid repeated freeze-thaw cycles. During use, minimize the time components are exposed to room temperature and return them promptly to -20°C; storage after handling. Do not store at elevated temperatures for extended periods.
Expiry Date
12 months under recommended storage conditions to ensure optimal performance.
Note
For bulk pricing or custom reagent inquiries, please contact us by email or phone. Products are shipped on ice via FedEx.
Restrictions
For Research Use Only (RUO). Not intended for diagnostic or therapeutic use.
Shipping
Shipped on ice under temperature-controlled conditions.
Background
Glutathione S-transferase Alpha 1 (GSTa1) is a cytosolic detoxification enzyme that catalyzes the conjugation of glutathione to electrophilic substrates. This reaction protects cells from oxidative damage and xenobiotic toxicity. GSTa1 expression is frequently studied as a biomarker of hepatic stress and metabolic adaptation.
Pathways
GSTa1 participates in the glutathione-dependent phase II detoxification pathway. It catalyzes conjugation reactions that neutralize reactive metabolites generated during xenobiotic metabolism, facilitating downstream elimination and maintaining cellular redox homeostasis.
For Research Use Only | Not For Clinical Use
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