MetaVital™ Rat Glutathione S-transferase A6 (GSTA6) ELISA Kit

CAT#: ITS-0326-WB40
Product Type: ELISA Kit
Species: Rat
Target: Rat Glutathione S-Transferase A6 (GSTA6)
Brand: MetaVital™
Development Stage: ADME
ADME Research Domain: Metabolism
Short Description
Quantitatively measures rat GSTA6 protein levels in biological samples using a sensitive sandwich ELISA assay.
Brand
MetaVital™
Development Stage
ADME
ADME Research Domain
Metabolism
Description
MetaVital™ Rat Glutathione S-Transferase A6 (GSTA6) ELISA Kit is a sensitive immunoassay designed for the quantitative detection of GSTA6 in rat biological samples. Utilizing a sandwich ELISA format with highly specific antibodies, this kit enables accurate measurement of GSTA6 in serum, plasma, tissue homogenates, and cell lysates, supporting investigations of detoxification processes, oxidative stress responses, and hepatic metabolism.
Features
High-specificity antibody pair ensures selective recognition of rat GSTA6, enabling reliable detection even in complex biological sample matrices.
Sensitive sandwich ELISA configuration provides strong signal amplification and a wide dynamic detection range for accurate protein quantification.
Optimized reagents and streamlined protocol support reproducible results and efficient processing of multiple experimental samples.
Compatible with diverse rat-derived sample types including serum, plasma, tissue homogenates, and cultured cell lysates for versatile laboratory applications.
Process Relevance
Quantifying GSTA6 supports evaluation of cellular detoxification activity and oxidative stress responses in experimental rat models.
Application Stage
Drug discovery, toxicology studies, metabolic pathway research, and biomarker analysis in preclinical rat systems.
Applications
Quantitative detection of GSTA6 in rat serum, plasma, tissue homogenates, and cell lysates for oxidative stress studies, detoxification research, toxicology investigations, ADME profiling studies, and biomarker evaluation.
Target
Rat Glutathione S-Transferase A6 (GSTA6)
Detection Method
Colorimetric
Sample Type
Tissue homogenates, cell lysates and other biological fluids.
Assay Measures
Quantitative
Research Areas
Oxidative stress biology, pharmacokinetics (ADME), detoxification mechanisms, drug metabolism, toxicology, liver metabolism research, biomarker discovery, etc.
Size
96 tests
Data Output Type
Quantitative protein concentration measurement using endpoint absorbance detection in a sandwich ELISA format.
Assay Range
0.156 ng/ml - 10 ng/ml
Species
Rat
Assay Measures
Quantitative
Storage
Upon receipt, store the kit in accordance with the storage conditions specified in the product manual.
Storage Comment
Avoid repeated freeze-thaw cycles. During use, minimize the time components are exposed to room temperature and return them promptly to -20°C; storage after handling. Do not store at elevated temperatures for extended periods.
Expiry Date
12 months under recommended storage conditions to ensure optimal performance.
Note
For bulk pricing or custom reagent inquiries, please contact us by email or phone. Products are shipped on ice via FedEx.
Restrictions
For Research Use Only (RUO). Not intended for diagnostic or therapeutic use.
Shipping
Shipped on ice under temperature-controlled conditions.
Background
Glutathione S-transferase A6 (GSTA6) belongs to the alpha class of GST enzymes that play essential roles in cellular detoxification. These enzymes catalyze the conjugation of reduced glutathione to electrophilic compounds, facilitating detoxification of xenobiotics and reactive metabolites. GSTA6 activity is particularly important in the liver, where it contributes to protection against oxidative and chemical stress.
Pathways
GSTA6 participates in the glutathione-mediated detoxification pathway, where it catalyzes conjugation reactions that neutralize reactive electrophiles and toxic metabolites. It functions alongside antioxidant enzymes and glutathione biosynthesis pathways to maintain cellular redox balance and support hepatic metabolic defense mechanisms.
For Research Use Only | Not For Clinical Use
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