AccuMetab™ Pig CYP3A39 Enzyme, Catalytically Active with Cytochrome b5

CAT#: ITS-0426-YL80
Product Type: Recombinant Phase I Metabolizing Enzyme
Brand: AccuMetab
Development Stage: ADME
ADME Research Domain: Metabolism
Short Description
Enhanced pig CYP3A39 for high-activity preclinical Phase I profiling.
Brand
AccuMetab
Development Stage
ADME
ADME Research Domain
Metabolism
Background
This b5-enhanced system accurately mimics the massive Phase I metabolic capacity found in the porcine GI tract and liver. It is highly recommended for researchers requiring maximum in vitro metabolite generation to validate swine as a surrogate for human oral drug absorption.
Key Features
Cytochrome b5 supplemented for max catalytic turnover; Mimics massive Phase I capacity of porcine GI tract; Essential for max metabolite yield in oral absorption studies; Replaces variable porcine liver/intestinal microsomes
Applications
Enhanced Drug Metabolism Studies, Species Comparison
Research Areas
ADME; Preclinical Toxicology
Species
Pig
Expression System
Recombinant enzymes prepared from E. coli and co-expressed with NADPH CYP-reductase.
Physical Form
Liquid
Size
1 nmol
Storage
-80°C
Storage Comment
When stored at -80°C, our product remains stable and retains full functional activity for up to 10 years.
Note
For bulk pricing or custom reagent inquiries, please contact us by email or phone. Products are shipped on ice via FedEx.
Restrictions
For Research Use Only (RUO). Not intended for diagnostic or therapeutic use.
Shipping
Our enzyme products are shipped at -80°C.
For Research Use Only | Not For Clinical Use
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