MetaVital™ Human Microsomal glutathione S-transferase 2 (MGST2) ELISA Kit

CAT#: ITS-0326-WB30
Product Type: ELISA Kit
Species: Human
Target: Human Microsomal Glutathione S-Transferase 2 (MGST2) protein
Brand: MetaVital™
Development Stage: ADME
ADME Research Domain: Metabolism
Short Description
Accurately quantifies MGST2 levels in human tissues, serum, and cell lysates for enzymatic and biomarker studies.
Brand
MetaVital™
Development Stage
ADME
ADME Research Domain
Metabolism
Description
MetaVital™ Human MGST2 ELISA Kit provides a sensitive, reliable solution for detecting and quantifying MGST2 in human samples. It facilitates research into oxidative stress, xenobiotic metabolism, and pharmacological investigations, offering high specificity and reproducibility for biomarker discovery and preclinical evaluation.
Features
High specificity for human MGST2, reducing cross-reactivity with other GST isoforms in complex biological matrices.
Broad dynamic range from 0.156-10 ng/mL enables accurate measurement in both low- and high-abundance samples.
Complete kit includes lyophilized standards, detection antibodies, and optimized reagents for reproducible, consistent assay performance.
Robust stability under recommended storage conditions ensures reliable experimental results over long-term studies and multiple batches.
Process Relevance
Supports precise monitoring of MGST2 levels to assess cellular detoxification and oxidative stress in human models.
Application Stage
Drug discovery, toxicology assessment, biomarker validation, and mechanistic enzymology studies.
Applications
Quantitative ELISA analysis of human serum, plasma, and tissue lysates; supports oxidative stress evaluation, drug metabolism studies, ADME profiling studies, and pathway investigation.
Qualified With
Internal performance validation using reference standards under defined assay conditions.
Target
Human Microsomal Glutathione S-Transferase 2 (MGST2) protein
Detection Method
Colorimetric
Sample Type
Tissue homogenates, cell lysates and other biological fluids.
Assay Measures
Quantitative
Research Areas
Pharmacology, pharmacokinetics (ADME), toxicology, oxidative stress biology, enzymology, drug metabolism, biomarker discovery, etc.
Size
96 tests
Data Output Type
Quantitative measurement of MGST2 protein concentration via colorimetric ELISA assay.
Assay Range
0.156 ng/ml - 10 ng/ml
Species
Human
Assay Measures
Quantitative
Storage
Upon receipt, store the kit in accordance with the storage conditions specified in the product manual.
Storage Comment
Avoid repeated freeze-thaw cycles. During use, minimize the time components are exposed to room temperature and return them promptly to -20°C; storage after handling. Do not store at elevated temperatures for extended periods.
Expiry Date
12 months under recommended storage conditions to ensure optimal performance.
Note
For bulk pricing or custom reagent inquiries, please contact us by email or phone. Products are shipped on ice via FedEx.
Restrictions
For Research Use Only (RUO). Not intended for diagnostic or therapeutic use.
Shipping
Shipped on ice under temperature-controlled conditions.
Background
MGST2 is a microsomal enzyme that catalyzes glutathione conjugation to reactive electrophilic intermediates, playing a key role in cellular detoxification. Its activity is essential for oxidative stress regulation and drug metabolism, providing critical insights in disease mechanism and therapeutic evaluation.
Pathways
MGST2 functions within the glutathione-dependent detoxification pathway, conjugating glutathione to reactive intermediates. Upstream oxidative stress signals induce expression, while downstream activity facilitates metabolite clearance and cytoprotection.
For Research Use Only | Not For Clinical Use
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