MetaVital™ Rat Glutathione S Transferase Mu 3 (GSTM3) ELISA Kit

CAT#: ITS-0326-WB31
Product Type: ELISA Kit
Species: Rat
Target: Rat Glutathione S Transferase Mu 3 (GSTM3) protein
Brand: MetaVital™
Development Stage: ADME
ADME Research Domain: Metabolism
Short Description
Quantitatively measures rat GSTM3 levels in biological samples for oxidative stress and detoxification research.
Brand
MetaVital™
Development Stage
ADME
ADME Research Domain
Metabolism
Description
MetaVital™ Rat Glutathione S Transferase Mu 3 (GSTM3) ELISA Kit provides a sensitive and reliable method for detecting GSTM3 protein levels in rat biological samples. Designed for research use, this assay supports studies of oxidative stress, xenobiotic metabolism, and cellular detoxification pathways in pharmacological and toxicological models.
Features
Highly specific antibody pair ensures selective detection of rat GSTM3 while minimizing cross-reactivity with other glutathione S-transferase family members.
Sensitive colorimetric ELISA format supports reliable detection of low-abundance GSTM3 protein across a broad concentration range.
Complete assay kit includes pre-coated microplate, standards, detection reagents, and buffers to simplify experimental setup and improve reproducibility.
Optimized assay workflow allows efficient processing of multiple samples simultaneously while maintaining strong signal consistency and analytical reliability.
Process Relevance
Facilitates monitoring of GSTM3 expression to evaluate detoxification capacity and oxidative stress responses in experimental rat models.
Application Stage
Preclinical drug discovery, toxicology studies, biomarker validation, and enzymatic pathway research.
Applications
Quantitative ELISA analysis of GSTM3 in rat serum, plasma, tissue homogenates, and cell lysates to investigate oxidative stress responses, detoxification mechanisms, ADME profiling, and drug metabolism.
Qualified With
Internal performance validation using reference standards under defined assay conditions.
Target
Rat Glutathione S Transferase Mu 3 (GSTM3) protein
Detection Method
Colorimetric
Sample Type
Tissue homogenates, cell lysates and other biological fluids.
Assay Measures
Quantitative
Research Areas
Drug metabolism, pharmacokinetics (ADME), toxicology, oxidative stress biology, pharmacology, enzymology, biomarker discovery, etc.
Size
96 tests
Data Output Type
Quantitative protein concentration measurement using a colorimetric endpoint ELISA assay.
Assay Range
0.156 ng/ml - 10 ng/ml
Species
Rat
Assay Measures
Quantitative
Storage
Upon receipt, store the kit in accordance with the storage conditions specified in the product manual.
Storage Comment
Avoid repeated freeze-thaw cycles. During use, minimize the time components are exposed to room temperature and return them promptly to -20°C; storage after handling. Do not store at elevated temperatures for extended periods.
Expiry Date
12 months under recommended storage conditions to ensure optimal performance.
Note
For bulk pricing or custom reagent inquiries, please contact us by email or phone. Products are shipped on ice via FedEx.
Restrictions
For Research Use Only (RUO). Not intended for diagnostic or therapeutic use.
Shipping
Shipped on ice under temperature-controlled conditions.
Background
Glutathione S-transferase Mu 3 (GSTM3) belongs to the mu class of cytosolic glutathione S-transferases involved in cellular defense against oxidative damage. These enzymes catalyze the conjugation of glutathione to electrophilic compounds, facilitating detoxification and protection against xenobiotic toxicity.
Pathways
GSTM3 functions in the glutathione-mediated phase II detoxification pathway, conjugating glutathione to reactive electrophiles produced during metabolism. This process supports downstream metabolite elimination and contributes to maintaining intracellular redox balance.
For Research Use Only | Not For Clinical Use
Online Inquiry