All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.
Focused on the recent advances in CAR structure design and manufacturing, Creative Biolabs is dedicated to improving the prospects for the future development of CAR-T cell therapy. Based on innovative manufacturing technology, we are developing a new Silence™ CAR platform that introduces gene-silencing elements to a CAR construct. To advance your CAR-T cell research, we offer a full range of service custom Silence™ CAR-T development, from Silence™ CAR design to cellular functional validation and expansion.
Fig.1 Silence™ CAR-T.
As pioneers in the next-generation CAR-T development, we provide one-stop Silence™ CAR-T development services, ranging from design, plasmid synthesis and construction, transfection, and expression evaluation to functional testing. Our Silence™ CAR-T platform combines the RNAi technology that silences genes by generating knockdown at the mRNA level. In order to verify the silencing effects as expected, we perform real-time qRT-PCR to test RNA expression level and Western blot to test protein expression level. We will take all testing details into consideration, such as positive/negative controls and the cell transfection efficiency.
Creative Biolabs has developed a variety of CAR-T products to make breakthroughs in cell therapies. We provide you with the overall solution covering the workflow of Silence™ CAR development. Our scientists can design and construct CARs including classical routes of CARs and special CARs. We are committed to being a trusted partner and providing you with the information you need. Once we know the details of your project, we offer scientific support as well as an overall solution to help get you started!
Fig.2 Workflow of Silence™ CAR-T therapy development.
Do not hesitate to contact us for a consultation on your project and study design.
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