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Lenti-gp100 TCR (T2(1)Cpost)-VP(VP-TCR-C406)

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The ready-to-use lentiviral particles of Lenti-gp100 TCR (T2(1)Cpost)-VP is packaged using 3rd generation of lentiviral packaging system, in which the gene of Mouse TCR will be driven by a CMV promotor. The target gene of TCR packaged in lentiviral particles could be used for high efficency tranduction of T cells and stably integrated expression.

Specifications

Type of Therapeutics
T cell receptor
Target
gp100
Clone
T2(1)Cpost
Promotor
CMV
Packaging System
Lentivirus
Packaging Cell
293T
Targeting Diseases
Pigmentary diseases

Target

Introduction
This gene encodes a melanocyte-specific type I transmembrane glycoprotein. The encoded protein is enriched in melanosomes, which are the melanin-producing organelles in melanocytes, and plays an essential role in the structural organization of premelanosomes. This protein is involved in generating internal matrix fibers that define the transition from Stage I to Stage II melanosomes. This protein undergoes a complex pattern of prosttranslational processing and modification that is essential to the proper functioning of the protein. A secreted form of this protein that is released by proteolytic ectodomain shedding may be used as a melanoma-specific serum marker. Alternate splicing results in multiple transcript variants.
Alternative Names
PMEL; premelanosome protein; SIL, SILV, silver (mouse homolog) like , silver homolog (mouse); melanocyte protein PMEL; D12S53E; gp100; Pmel17; SI; TCR; T cell receptor; transgenic TCR; antigen-specific T cell receptors; Engineering T-cell receptors; recombinant t cell receptors; specific t cell receptor; modified t cell receptor; retroviral vector; Melanoma
Gene ID
6490

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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OthersCarcinoma Kits for CARs/TCRs Development 

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USA: 1-631-381-2994
Europe: 44-207-097-1828
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CONTACT US

USA
45-1 Ramsey Road, Shirley, NY 11967, USA
Tel: 1-631-381-2994
Fax: 1-631-207-8356
Email:

Europe
Ringstrasse 4, 64401 Gross-Bieberau, Germany
Tel: 44-207-097-1828

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