PSMA

Prostate-specific membrane antigen (PSMA) is also known as glutamate carboxypeptidase II (GCPII), N-acetyl-L-aspartyl-L-glutamate peptidase I (NAALADase I) or NAAG peptidase. It is a zinc metalloenzyme that locates in membranes, which mainly expressed in the tissues of prostate epithelium, the proximal tubules of the kidney, the jejunal brush border of the small intestine and ganglia of the nervous system. PSMA is associated with prostate cancer as well as neovasculature of most of solid tumors.

Associated Disease

CAR Vector Products Product list:

Catalog Targeting
Cell Type
Generation Antibody
Clone
Vector
Length
Vector
Type
Vector Design Antibody
Host
Data
sheet
Price
CAR-LC362 T cell Second HuJ591 ~8kb Retroviral scFv (PSMA)-CD28-41BB/scFv (CD19)-CD3ζ Human Inquiry
CAR-LC385 T cell First HuJ591 ~8kb Retroviral scFv-PD1 Human Inquiry
CAR-LC386 T cell First HuJ592 ~8kb Retroviral scFv-CTLA4 Human Inquiry
CAR-LC387 T cell First HuJ593 ~8kb Retroviral scFv-LAG3 Human Inquiry
CAR-LC388 T cell First HuJ594 ~8kb Retroviral scFv-2B4 Human Inquiry
CAR-MZ034 T cell Second HuJ595 ~8kb Retroviral scFv-PD-1-CD3ζ Human Inquiry
CAR-MZ035 T cell Second HuJ596 ~8kb Retroviral scFv-CTLA4-CD3ζ Human Inquiry
CAR-T-1-L336-2 T cell First J591 8kb Lentiviral scFv-CD28 Human Inquiry
CAR-T-1-L336-G T cell First J591 8kb Lentiviral scFv-FcεRIγ Human Inquiry
CAR-T-1-L336-Z T cell First J591 8kb Lentiviral scFv-CD3ζ Human Inquiry
CAR-T-2-L336-2G T cell Second J591 8kb Lentiviral scFv-CD28-FcεRIγ Human Inquiry
CAR-T-2-L336-2Z T cell Second J591 8kb Lentiviral scFv-CD28-CD3ζ Human Inquiry
CAR-T-2-L336-4G T cell Second J591 8kb Lentiviral scFv-CD4-FcεRIγ Human Inquiry
CAR-T-2-L336-4Z T cell Second J591 8kb Lentiviral scFv-CD4-CD3ζ Human Inquiry
CAR-T-2-L336-8Z T cell Second J591 8kb Lentiviral scFv-CD8-CD3ζ Human Inquiry
CAR-T-2-L336-BZ T cell Second J591 8kb Lentiviral scFv-41BB-CD3ζ Human Inquiry
CAR-T-2-L336-CZ T cell Second J591 8kb Lentiviral scFv-b2c-CD3ζ Human Inquiry
CAR-T-3-L336-2BZ T cell Third J591 8kb Lentiviral scFv-CD28-41BB-CD3ζ Human Inquiry
CAR-T-3-L336-2XZ T cell Third J591 8kb Lentiviral scFv-CD28-OX40-CD3ζ Human Inquiry

CAR Viral Particles Product list:

Catalog Antibody
Clone
Packaging
System
Generation Gene
Construct
Promotor Packaging
Cell
Titer Data
sheet
Price
VP-CAR-LC413 J591 Lentivirus First scFv (J591)-CD28 CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC414 J591 Lentivirus First scFv (J591)-FcεRIγ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC415 J591 Lentivirus First scFv (J591)-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC416 J591 Lentivirus Second scFv (J591)-CD28-FcεRIγ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC417 J591 Lentivirus Second scFv (J591)-CD28-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC418 J591 Lentivirus Second scFv (J591)-CD4-FcεRIγ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC419 J591 Lentivirus Second scFv (J591)-CD4-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC420 J591 Lentivirus Second scFv (J591)-CD8-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC421 J591 Lentivirus Second scFv (J591)-41BB-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC422 J591 Lentivirus Second scFv (J591)-b2c-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC423 J591 Lentivirus Third scFv (J591)-CD28-41BB-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC424 J591 Lentivirus Third scFv (J591)-CD28-OX40-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
CONTACT US

USA
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Tel: 1-631-871-5806
Fax: 1-631-207-8356
Email:

Europe
Ringstrasse 4, 64401 Gross-Bieberau, Germany
Tel: 44-207-048-3343

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