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PSMA

Prostate-specific membrane antigen (PSMA) is also known as glutamate carboxypeptidase II (GCPII), N-acetyl-L-aspartyl-L-glutamate peptidase I (NAALADase I) or NAAG peptidase. It is a zinc metalloenzyme that locates in membranes, which mainly expressed in the tissues of prostate epithelium, the proximal tubules of the kidney, the jejunal brush border of the small intestine and ganglia of the nervous system. PSMA is associated with prostate cancer as well as neovasculature of most of solid tumors.

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