Creative Biolabs has a tradition of commitment. To achieve efficient execution and regulatory approval, we offer careful considerations of your program for the development of a cellular or gene therapy product – now and in the future.
EXPLORE MORE HighlightsWe focus on unmet needs and develop novel cellular and gene drugs and solutions that offer significant benefits over existing options.
EXPLORE MORE HighlightsThe advent of Chimeric Antigen Receptor T-cell (CAR-T) therapies has revolutionized the field of oncology, providing new avenues for treating various forms of cancer. Our 20 years of experience in the biotechnology sector have equipped us with the expertise and technological capabilities to support the entire lifecycle of CAR-T products, from early development to commercialization.
EXPLORE MORETo accelerate advanced breakthroughs of your projects, we offer broad range of platforms which enable our clients be free to tackle problems with cutting-edge technologies from different angles and in different methods.
EXPLORE MORE HighlightsUse the resources in our library to help you understand your options and make critical decisions for your study. We offer oncolytic virus, CAR-T, and dendritic cell related documents, as well as newsletter. If you don't find the answers you're looking for, contact us for additional assistance.
EXPLORE MORE HighlightsGet a real taste and understanding of the business and culture of one of the world's great research-based cellular and gene therapy discovery and development companies.
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As a biotechnology company at the forefront of immunotherapy development field, Creative Biolabs provides TCR clinical therapeutics services. Our experts can construct TCR targeting antigen of your interest, engineer T cells and also perform the validation assessment of TCR-engineered T cells. Our procedures can meet the rigorous quality control standards which make our products qualified for both the preclinical and clinical trials.
T cell, also known as T lymphocyte, is a type of leukocyte and it plays critical roles in cell-mediated immunity, playing an important role in defense against diverse tumor cells and pathogenic organisms inside biological body. Although T-cell function is regulated by means of plenty interactions with other cell types and soluble factors, the T-cell receptor (TCR) is the only structure on the T-cell surface that defines its antigen-recognition potential. Consequently, autologous or donor-derived T-lymphocyte populations can be equipped with a TCR of defined specificity in short term ex vivo cultures, and re-infusion of the redirected cells would be used as a strategy for the immune therapy against various cancers and infection diseases. In this immunotherapy strategy, TCR gene transfer would permit the instantaneous generation of defined T-cell immunity and therapeutic quantities of antigen specific T cells can be created within a short period of time. Moreover, TCR gene therapy would allow the introduction of TCRs which have specificities that are not present naturally, and thereby provide a strategy to circumvent the limitation of the endogenous T-cell repertoire.
With a deep understanding of the principle of TCR gene transfer therapy, Creative Biolabs has great technical power and enriched experience to offer customers top-quality TCR clinical therapeutics services. Based on a great amount of research, scientists of Creative Biolabs have generated a series of TCR constructs, either isolated from certain donor people or constructed by using recombinant technology. And we are capable of engrafting those TCRs onto T cells or invariant natural killer T (iNKT) cells to generate modified T cells with desired specificity and efficacy. Our TCR platform can be widely applied for immunotherapy of various human malignancies, autoimmune diseases and viral diseases or multiply animal models researches and clinical trials.
Creative Biolabs is promoting the translation of high quality immunotherapy technology from laboratories into clinical trials around the world, and it's our pleasure to offer you the best service in order to greatly accelerate your researches.
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All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.
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NEW SOLUTION
CellRapeutics™ In Vivo Cell Engineering: One-stop in vivo T/B/NK cell and macrophage engineering services covering vectors construction to function verification.
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NOVEL TECHNOLOGY
Silence™ CAR-T Cell: A novel platform to enhance CAR-T cell immunotherapy by combining RNAi technology to suppress genes that may impede CAR functionality.
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Canine CAR-T Therapy Development: From early target discovery, CAR design and construction, cell culture, and transfection, to in vitro and in vivo function validation.
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