MetaVital™ Mouse Glutathione S-transferase theta-4 (GSTT4) ELISA Kit

CAT#: ITS-0326-WB42
Product Type: ELISA Kit
Species: Mouse
Target: Glutathione S-transferase theta-4 (GSTT4)
Brand: MetaVital™
Development Stage: ADME
ADME Research Domain: Metabolism
Short Description
Quantitatively measures mouse GSTT4 protein levels in biological samples using a sensitive sandwich ELISA assay.
Brand
MetaVital™
Development Stage
ADME
ADME Research Domain
Metabolism
Description
MetaVital™ Mouse Glutathione S-Transferase Theta-4 (GSTT4) ELISA Kit is a high-sensitivity immunoassay developed for the quantitative detection of GSTT4 in mouse biological samples. Utilizing a sandwich ELISA format with highly specific antibodies, this kit enables accurate measurement of GSTT4 in serum, plasma, tissue extracts, and cell lysates, supporting studies on detoxification pathways, oxidative stress responses, and xenobiotic metabolism.
Features
High-affinity antibody pair provides selective recognition of mouse GSTT4, ensuring reliable detection with minimal interference from related glutathione S-transferase family members.
Sensitive sandwich ELISA configuration delivers strong signal amplification and broad dynamic detection range for accurate and reproducible protein quantification.
Optimized reagents and standardized protocol streamline assay workflow, enabling efficient processing of multiple samples with consistent experimental performance.
Compatible with multiple mouse-derived sample types including serum, plasma, tissue homogenates, and cultured cell lysates for flexible experimental applications.
Process Relevance
Monitoring GSTT4 levels supports evaluation of detoxification capacity and oxidative stress responses in experimental mouse models.
Application Stage
Drug discovery, toxicology evaluation, metabolic pathway research, and biomarker analysis in mouse-based preclinical studies.
Applications
Quantitative detection of GSTT4 in mouse serum, plasma, tissue homogenates, and cell lysates for oxidative stress analysis, detoxification pathway studies, toxicology research, ADME profiling studies, and biomarker discovery.
Target
Glutathione S-transferase theta-4 (GSTT4)
Detection Method
Colorimetric
Sample Type
GSTT4, a detoxification enzyme involved in xenobiotic metabolism.
Assay Measures
Quantitative
Research Areas
Oxidative stress biology, pharmacokinetics (ADME), xenobiotic metabolism, drug metabolism, toxicology, liver function research, biomarker discovery, etc.
Size
96 tests
Data Output Type
Quantitative protein concentration measurement using endpoint absorbance detection in a sandwich ELISA assay.
Assay Range
0.156 ng/ml - 10 ng/ml
Species
Mouse
Assay Measures
Quantitative
Storage
Upon receipt, store the kit in accordance with the storage conditions specified in the product manual.
Storage Comment
Avoid repeated freeze-thaw cycles. During use, minimize the time components are exposed to room temperature and return them promptly to -20°C; storage after handling. Do not store at elevated temperatures for extended periods.
Expiry Date
12 months under recommended storage conditions to ensure optimal performance.
Note
For bulk pricing or custom reagent inquiries, please contact us by email or phone. Products are shipped on ice via FedEx.
Restrictions
For Research Use Only (RUO). Not intended for diagnostic or therapeutic use.
Shipping
Shipped on ice under temperature-controlled conditions.
Background
Glutathione S-transferases (GSTs) are a family of detoxification enzymes that protect cells from oxidative damage and chemical stress. Members of the theta class, including GSTT4, catalyze the conjugation of reduced glutathione to reactive electrophilic compounds. This process supports cellular defense against toxic metabolites generated during normal metabolism or xenobiotic exposure.
Pathways
GSTT4 functions within glutathione-dependent detoxification pathways, catalyzing conjugation reactions that neutralize electrophilic intermediates. It works in coordination with glutathione biosynthesis enzymes and antioxidant defense systems to maintain cellular redox balance and protect against oxidative stress.
For Research Use Only | Not For Clinical Use
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