MetaVital™ Rat Glutathione S Transferase Mu 5 (GSTM5) ELISA Kit

CAT#: ITS-0326-WB41
Product Type: ELISA Kit
Species: Rat
Target: Rat Glutathione S Transferase Mu 5 (GSTM5)
Brand: MetaVital™
Development Stage: ADME
ADME Research Domain: Metabolism
Short Description
Quantitatively measures rat GSTM5 protein levels in biological samples using a sensitive sandwich ELISA assay.
Brand
MetaVital™
Development Stage
ADME
ADME Research Domain
Metabolism
Description
MetaVital™ Rat Glutathione S Transferase Mu 5 (GSTM5) ELISA Kit is a high-sensitivity immunoassay designed for the quantitative detection of GSTM5 in rat biological samples. Based on a sandwich ELISA format with highly specific antibodies, this kit enables accurate measurement of GSTM5 in serum, plasma, tissue homogenates, and cell lysates, supporting research on detoxification pathways, oxidative stress responses, and xenobiotic metabolism.
Features
Highly specific antibody pair ensures selective recognition of rat GSTM5, providing reliable detection with minimal cross-reactivity in complex biological samples.
Sensitive sandwich ELISA configuration delivers strong signal amplification and a broad dynamic detection range for precise protein quantification.
Pre-optimized reagents and standardized assay workflow support reproducible results and efficient processing of multiple samples in parallel.
Compatible with various rat-derived sample types including serum, plasma, tissue homogenates, and cell culture lysates for flexible experimental design.
Process Relevance
Quantifying GSTM5 supports evaluation of detoxification enzyme activity and oxidative stress responses in experimental toxicology and pharmacology studies.
Application Stage
Drug discovery, toxicology research, metabolic pathway analysis, and biomarker evaluation in preclinical rat models.
Applications
Quantitative detection of GSTM5 in rat serum, plasma, tissue homogenates, and cell lysates for oxidative stress studies, detoxification pathway analysis, toxicology research, ADME profiling studies, and biomarker discovery.
Target
Rat Glutathione S Transferase Mu 5 (GSTM5)
Detection Method
Colorimetric
Sample Type
Tissue homogenates, cell lysates and other biological fluids.
Assay Measures
Quantitative
Research Areas
Oxidative stress biology, pharmacokinetics (ADME), xenobiotic metabolism, toxicology, pharmacology, liver metabolism research, biomarker discovery, etc.
Size
96 tests
Data Output Type
Quantitative protein concentration measurement using endpoint absorbance detection in a sandwich ELISA assay.
Assay Range
0.156 ng/ml - 10 ng/ml
Species
Rat
Assay Measures
Quantitative
Storage
Upon receipt, store the kit in accordance with the storage conditions specified in the product manual.
Storage Comment
Avoid repeated freeze-thaw cycles. During use, minimize the time components are exposed to room temperature and return them promptly to -20°C; storage after handling. Do not store at elevated temperatures for extended periods.
Expiry Date
12 months under recommended storage conditions to ensure optimal performance.
Note
For bulk pricing or custom reagent inquiries, please contact us by email or phone. Products are shipped on ice via FedEx.
Restrictions
For Research Use Only (RUO). Not intended for diagnostic or therapeutic use.
Shipping
Shipped on ice under temperature-controlled conditions.
Background
Glutathione S-transferase Mu 5 (GSTM5) belongs to the mu class of GST enzymes involved in cellular detoxification. These enzymes catalyze conjugation reactions between reduced glutathione and electrophilic compounds, facilitating elimination of toxic metabolites. GSTM5 plays an important role in protecting cells from oxidative damage and chemical stress.
Pathways
GSTM5 functions within the glutathione-mediated detoxification pathway, catalyzing the conjugation of glutathione to reactive xenobiotic intermediates. This activity supports antioxidant defense systems and cooperates with glutathione synthesis and redox-regulating enzymes to maintain cellular homeostasis.
For Research Use Only | Not For Clinical Use
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