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Disease-specific Stem Cell Therapy Development


Disease-specific stem cell therapy development

Research on stem cells began in the late 19th century in Europe. The term stem cell was coined to describe the fertilized egg that becomes an organism. In the U.S., the adult stem cells were studied in the 1950s. A cancer researcher found large tumors in the scrotums of mice that contained mixtures of differentiated and undifferentiated cells. It concluded that these cells were pluripotent, and they could differentiate into any cells. In 1968, the first successful bone marrow transplant was performed on a child who suffers from an immune deficiency. Subsequently, the methods to derive ESCs from mouse embryos discovered and the method to take stem cells from a human embryo and grow them in a laboratory was developed. Adult and embryonic stem cells, nowadays, are able to treat cancer, Parkinson’s disease, baldness, Alzheimer’s disease, sclerosis, blindness, Type 1 diabetes, muscle damage and neurological disorders, and many others.

The aim of any stem-cell therapy could lead to cures for a myriad of diseases afflicting humans, and to repair a damaged tissue that can't heal itself. Stem cell therapies not only simply transplanting cells into the body but also be possible to stimulate stem cells already in the body to directing them to grow new, healthy tissue. The isolation of stem and progenitors cells is now being developed for many clinical applications. In Creative Biolabs, the services of disease-specific stem cell therapy development provide various stem cells which correspond to different types of disease.

Disease-specific stem cell therapy development

Disease-specific Stem Cells Therapy

Most of the therapeutic mechanism of regenerative medicine action was defined and wide-ranging toxicology studies were done for the stem cells therapy. Also, with the improving of proper standardization and characterization of transplanted cell preparations, the stem cell therapies have demonstrated therapeutic efficacy and benefit in preclinical models through paracrine mechanisms or differentiation. Since target disease will probably influence which of these mechanisms is more important, the stem cells which specific to different diseases are necessary to advance the field. At Creative Biolabs, the disease-specific stem cell therapy development service provide more choices to our customers upon different demands.

Disease-specific stem cell therapy development

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Two-color viability assays

Cardiovascular Diseases

Single viability assays

Neurodegenerative Diseases

Single viability assays

Neurological Diseases

Two-color viability assays

Autoimmune Diseases

Single viability assays

Ophthalmological Diseases

Single viability assays

Renal Diseases

Two-color viability assays

Liver Diseases

Single viability assays

Skin conditions

Single viability assays

Degenerative Skeletal Diseases

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References

  1. Trounson, A., & McDonald, C. (2015). Stem Cell Therapies in Clinical Trials: Progress and Challenges. Cell Stem Cell, 17(1), 11-22. doi: 10.1016/j.stem.2015.06.007.
  2. Edwards, R. (2001). IVF and the history of stem cells. Nature, 413(6854), 349-351. doi: 10.1038/35096649.

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