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CD123

CD123(Cluster of Differentiation 123) usually know as Interleukin 3 receptor alpha chain(IL3RA) is a transmembrane protein of 41.3 KDa. It has been shown to interact with Interleukin 3, a pleiotropic cytokine, mainly produced by activated T-lymphocytes, regulating the function and production of hematopoietic and immune cell. CD123 is overexpressed in various hematologic malignancies, including a part of acute myeloid and B-lymphoid leukemias, blastic plasmocytoid dendritic neoplasms (BPDCN) and hairy cell leukemia. Elevated IL-3Ra expression has been reported in about 45% of patients with acute myeloid leukemia and in 40% of patients with acute B lymphoid leukemia. An high IL-3Ra expression has been reported also in hairy cell leukemia.

Associated Disease
  • CAR Vector Products
  • CAR Viral Particles
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CAT Product Name Target SpeciesAntibody CloneAntibody HostReceptor ConstructionVector TypeTargeting Cell Type Inquiry & Datasheet
CAR-T-1-M306-2 Anti-CD123 scFv h(CD28) CART, pCDCAR1 Human 7G3 Mouse scFv-CD28 Lentiviral T cell   Add to Cart   Datasheet
CAR-T-1-M306-G Anti-CD123 scFv h(FcεRIγ) CART, pCDCAR1 Human 7G3 Mouse scFv-FcεRIγ Lentiviral T cell   Add to Cart   Datasheet
CAR-T-1-M306-Z Anti-CD123 scFv h(CD3ζ) CART, pCDCAR1 Human 7G3 Mouse scFv-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-T-2-M306-2G Anti-CD123 scFv h(CD28-FcεRIγ) CART, pCDCAR1 Human 7G3 Mouse scFv-CD28-FcεRIγ Lentiviral T cell   Add to Cart   Datasheet
CAR-T-2-M306-2Z Anti-CD123 scFv h(CD28-CD3ζ) CART, pCDCAR1 Human 7G3 Mouse scFv-CD28-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-T-2-M306-4G Anti-CD123 scFv h(CD4-FcεRIγ) CART, pCDCAR1 Human 7G3 Mouse scFv-CD4-FcεRIγ Lentiviral T cell   Add to Cart   Datasheet
CAR-T-2-M306-4Z Anti-CD123 scFv h(CD4-CD3ζ) CART, pCDCAR1 Human 7G3 Mouse scFv-CD4-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-T-2-M306-8Z Anti-CD123 scFv h(CD8-CD3ζ) CART, pCDCAR1 Human 7G3 Mouse scFv-CD8-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-T-2-M306-BZ Anti-CD123 scFv h(41BB-CD3ζ) CART, pCDCAR1 Human 7G3 Mouse scFv-41BB-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-LC028 Anti-CD123 (26292) h(CD28-CD3ζ) CAR, pCDCAR1 Human 26292 Human scFv-CD28-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-T-2-M306-CZ Anti-CD123 scFv h(b2c-CD3ζ) CART, pCDCAR1 Human 7G3 Mouse scFv-b2c-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-T-3-M306-2BZ Anti-CD123 scFv h(CD28-41BB-CD3ζ) CART, pCDCAR1 Human 7G3 Mouse scFv-CD28-41BB-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-T-3-M306-2XZ Anti-CD123 scFv h(CD28-OX40-CD3ζ) CART, pCDCAR1 Human 7G3 Mouse scFv-CD28-OX40-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-LC029 Anti-CD123 (32716) h(CD28-CD3ζ) CAR, pCDCAR1 Human 32716 Human scFv-CD28-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-MZ023 Anti-CD123 (Clone 32716) h(41BB-CD3ζ) CAR, pCDCAR1 Human Clone 32716 Mouse scFv-41BB-CD3ζ Retroviral T cell   Add to Cart   Datasheet
CAR-MZ024 Anti-CD123 (Clone 26292) h(41BB-CD3ζ) CAR, pCDCAR1 Human Clone 26292 Mouse scFv-41BB-CD3ζ Retroviral T cell   Add to Cart   Datasheet
CAR-LC175 Anti-CD123 (Klon43) h(41BB-CD3ζ) CAR, pCDCAR1 Human Klon43 Human scFv-41BB-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-YF023 Anti-CD123 (CBL-YF004) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human CBL-YF004 Humanized scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-YF024 Anti-CD123 (CBL-YF004) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBL-YF004 Humanized scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-YF167 Anti-CD123 (CBL-YF054) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human CBL-YF054 Human scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-YF168 Anti-CD123 (CBL-YF054) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBL-YF054 Human scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-YF151 Anti-CD123 (CBL-YF046) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human CBL-YF046 Humanized scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-YF152 Anti-CD123 (CBL-YF046) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBL-YF046 Humanized scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP066 Anti-CD123 h(41BB-CD3ζ) CAR, pCDCAR1 Human Mouse scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP067 Anti-CD123 h(CD28-CD3ζ) CAR, pCDCAR1 Human Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP848 Anti-CD123 (old4) h(CD28-CD3ζ) CAR, pCDCAR1 Human old4 Humanized scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP889 Anti-CD123 (8E11C5) h(41BB-CD3ζ) CAR, pCDCAR1 Human 8E11C5 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP890 Anti-CD123 (6H2E3F3) h(CD28-CD3ζ) CAR, pCDCAR1 Human 6H2E3F3 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP849 Anti-CD123 (old4) h(41BB-CD3ζ) CAR, pCDCAR1 Human old4 Humanized scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP850 Anti-CD123 (12F1) h(CD28-CD3ζ) CAR, pCDCAR1 Human 12F1 Humanized scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP891 Anti-CD123 (6H2E3F3) h(41BB-CD3ζ) CAR, pCDCAR1 Human 6H2E3F3 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP892 Anti-CD123 (5B11) h(CD28-CD3ζ) CAR, pCDCAR1 Human 5B11 Rat scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP851 Anti-CD123 (12F1) h(41BB-CD3ζ) CAR, pCDCAR1 Human 12F1 Humanized scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP852 Anti-CD123 (3E3-D3) h(CD28-CD3ζ) CAR, pCDCAR1 Human 3E3-D3 Humanized scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP893 Anti-CD123 (5B11) h(41BB-CD3ζ) CAR, pCDCAR1 Human 5B11 Rat scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP894 Anti-CD123 (6H6) h(CD28-CD3ζ) CAR, pCDCAR1 Human 6H6 Rat scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP853 Anti-CD123 (3E3-D3) h(41BB-CD3ζ) CAR, pCDCAR1 Human 3E3-D3 Humanized scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP854 Anti-CD123 (1E1-G5) h(CD28-CD3ζ) CAR, pCDCAR1 Human 1E1-G5 Humanized scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP895 Anti-CD123 (6H6) h(41BB-CD3ζ) CAR, pCDCAR1 Human 6H6 Rat scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP896 Anti-CD123 (32703) h(CD28-CD3ζ) CAR, pCDCAR1 Human 32703 Rat scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet

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