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CD123

CD123(Cluster of Differentiation 123) usually know as Interleukin 3 receptor alpha chain(IL3RA) is a transmembrane protein of 41.3 KDa. It has been shown to interact with Interleukin 3, a pleiotropic cytokine, mainly produced by activated T-lymphocytes, regulating the function and production of hematopoietic and immune cell. CD123 is overexpressed in various hematologic malignancies, including a part of acute myeloid and B-lymphoid leukemias, blastic plasmocytoid dendritic neoplasms (BPDCN) and hairy cell leukemia. Elevated IL-3Ra expression has been reported in about 45% of patients with acute myeloid leukemia and in 40% of patients with acute B lymphoid leukemia. An high IL-3Ra expression has been reported also in hairy cell leukemia.

Associated Disease
  • CAR Vector Products
  • CAR Viral Particles
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CAT Product Name Target SpeciesAntibody CloneAntibody HostReceptor ConstructionVector TypeTargeting Cell Type Inquiry & Datasheet
CAR-T-1-M306-2 Anti-CD123 scFv h(CD28) CART, pCDCAR1 Human 7G3 Mouse scFv-CD28 Lentiviral T cell   Add to Cart   Datasheet
CAR-T-1-M306-G Anti-CD123 scFv h(FcεRIγ) CART, pCDCAR1 Human 7G3 Mouse scFv-FcεRIγ Lentiviral T cell   Add to Cart   Datasheet
CAR-T-1-M306-Z Anti-CD123 scFv h(CD3ζ) CART, pCDCAR1 Human 7G3 Mouse scFv-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-ZP866 Anti-CD123 (6C10-C4) h(CD28-CD3ζ) CAR, pCDCAR1 Human 6C10-C4 Humanized scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP867 Anti-CD123 (6C10-C4) h(41BB-CD3ζ) CAR, pCDCAR1 Human 6C10-C4 Humanized scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP868 Anti-CD123 (6D6-B8) h(CD28-CD3ζ) CAR, pCDCAR1 Human 6D6-B8 Humanized scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP869 Anti-CD123 (6D6-B8) h(41BB-CD3ζ) CAR, pCDCAR1 Human 6D6-B8 Humanized scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP870 Anti-CD123 (8B11-B7) h(CD28-CD3ζ) CAR, pCDCAR1 Human 8B11-B7 Humanized scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP871 Anti-CD123 (8B11-B7) h(41BB-CD3ζ) CAR, pCDCAR1 Human 8B11-B7 Humanized scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP872 Anti-CD123 (9B8-G6) h(CD28-CD3ζ) CAR, pCDCAR1 Human 9B8-G6 Humanized scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP873 Anti-CD123 (9B8-G6) h(41BB-CD3ζ) CAR, pCDCAR1 Human 9B8-G6 Humanized scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP874 Anti-CD123 (9D7-C8) h(CD28-CD3ζ) CAR, pCDCAR1 Human 9D7-C8 Humanized scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP875 Anti-CD123 (9D7-C8) h(41BB-CD3ζ) CAR, pCDCAR1 Human 9D7-C8 Humanized scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP876 Anti-CD123 (9F6-G3) h(CD28-CD3ζ) CAR, pCDCAR1 Human 9F6-G3 Humanized scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP877 Anti-CD123 (9F6-G3) h(41BB-CD3ζ) CAR, pCDCAR1 Human 9F6-G3 Humanized scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP878 Anti-CD123 (9G52) h(CD28-CD3ζ) CAR, pCDCAR1 Human 9G52 Rat scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP879 Anti-CD123 (9G52) h(41BB-CD3ζ) CAR, pCDCAR1 Human 9G52 Rat scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP880 Anti-CD123 (5B11) h(CD28-CD3ζ) CAR, pCDCAR1 Human 5B11 Rat scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP907 Anti-CD123 (LAB11) h(41BB-CD3ζ) CAR, pCDCAR1 Human LAB11 Rat scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP908 Anti-CD123 (LAB2) h(CD28-CD3ζ) CAR, pCDCAR1 Human LAB2 Rat scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP909 Anti-CD123 (LAB2) h(41BB-CD3ζ) CAR, pCDCAR1 Human LAB2 Rat scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP910 Anti-CD123 (LAC11) h(CD28-CD3ζ) CAR, pCDCAR1 Human LAC11 Rat scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP911 Anti-CD123 (LAC11) h(41BB-CD3ζ) CAR, pCDCAR1 Human LAC11 Rat scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP912 Anti-CD123 (LAC12) h(CD28-CD3ζ) CAR, pCDCAR1 Human LAC12 Rat scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP913 Anti-CD123 (LAC12) h(41BB-CD3ζ) CAR, pCDCAR1 Human LAC12 Rat scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP914 Anti-CD123 (LAE4) h(CD28-CD3ζ) CAR, pCDCAR1 Human LAE4 Rat scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP915 Anti-CD123 (LAE4) h(41BB-CD3ζ) CAR, pCDCAR1 Human LAE4 Rat scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP916 Anti-CD123 (LAF7) h(CD28-CD3ζ) CAR, pCDCAR1 Human LAF7 Rat scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP917 Anti-CD123 (LAF7) h(41BB-CD3ζ) CAR, pCDCAR1 Human LAF7 Rat scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP918 Anti-CD123 (LAF5) h(CD28-CD3ζ) CAR, pCDCAR1 Human LAF5 Rat scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP919 Anti-CD123 (LAF5) h(41BB-CD3ζ) CAR, pCDCAR1 Human LAF5 Rat scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP920 Anti-CD123 (LAG12) h(CD28-CD3ζ) CAR, pCDCAR1 Human LAG12 Rat scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP921 Anti-CD123 (LAG12) h(41BB-CD3ζ) CAR, pCDCAR1 Human LAG12 Rat scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP922 Anti-CD123 (LAH3) h(CD28-CD3ζ) CAR, pCDCAR1 Human LAH3 Rat scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP923 Anti-CD123 (LAH3) h(41BB-CD3ζ) CAR, pCDCAR1 Human LAH3 Rat scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP6897 Anti-CD123 (32716) h(iMC; iRC9) DS CAR, pCDCAR1 Human 32716 Mouse Dual-Switch CAR(CD123 scFv-MyD88-CD40-FKBP-CD3ζ; ∆CD19-FKBP12-caspase-9) Lentiviral vector T cell   Add to Cart   Datasheet
CAR-YF405 Anti-CD123 (32716) h(-CD3ζ) CAR, pCDCAR1 Human 32716 Mouse scFv-CD3ζ Lentiviral vector T Cell   Add to Cart   Datasheet
CAR-YF406 Anti-CD123 (32716) h(CD28-41BB-CD3ζ) CAR, pCDCAR1 Human 32716 Mouse scFv-CD28-41BB-CD3ζ Lentiviral vector T Cell   Add to Cart   Datasheet
CAR-ZP8826 Anti-CD123 (BA0185) h(CD28-CD3ζ) mRNA CAR, pcDCAR1 EBV BA0185 Rabbit scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP8827 Anti-CD123 (BA0185) h(4-1BB-CD3ζ) mRNA CAR, pcDCAR1 EBV BA0185 Rabbit scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet

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