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CD123

CD123(Cluster of Differentiation 123) usually know as Interleukin 3 receptor alpha chain(IL3RA) is a transmembrane protein of 41.3 KDa. It has been shown to interact with Interleukin 3, a pleiotropic cytokine, mainly produced by activated T-lymphocytes, regulating the function and production of hematopoietic and immune cell. CD123 is overexpressed in various hematologic malignancies, including a part of acute myeloid and B-lymphoid leukemias, blastic plasmocytoid dendritic neoplasms (BPDCN) and hairy cell leukemia. Elevated IL-3Ra expression has been reported in about 45% of patients with acute myeloid leukemia and in 40% of patients with acute B lymphoid leukemia. An high IL-3Ra expression has been reported also in hairy cell leukemia.

Associated Disease
  • CAR Vector Products
  • CAR Viral Particles
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CAT Product Name Target SpeciesAntibody CloneAntibody HostReceptor ConstructionVector TypeTargeting Cell Type Inquiry & Datasheet
CAR-ZP874 Anti-CD123 (9D7-C8) h(CD28-CD3ζ) CAR, pCDCAR1 Human 9D7-C8 Humanized scFv-CD28-CD3ζ Lentiviral vector T cell   Inquiry
  Datasheet
CAR-ZP875 Anti-CD123 (9D7-C8) h(41BB-CD3ζ) CAR, pCDCAR1 Human 9D7-C8 Humanized scFv-41BB-CD3ζ Lentiviral vector T cell   Inquiry
  Datasheet
CAR-ZP876 Anti-CD123 (9F6-G3) h(CD28-CD3ζ) CAR, pCDCAR1 Human 9F6-G3 Humanized scFv-CD28-CD3ζ Lentiviral vector T cell   Inquiry
  Datasheet
CAR-ZP877 Anti-CD123 (9F6-G3) h(41BB-CD3ζ) CAR, pCDCAR1 Human 9F6-G3 Humanized scFv-41BB-CD3ζ Lentiviral vector T cell   Inquiry
  Datasheet
CAR-ZP878 Anti-CD123 (9G52) h(CD28-CD3ζ) CAR, pCDCAR1 Human 9G52 Rat scFv-CD28-CD3ζ Lentiviral vector T cell   Inquiry
  Datasheet
CAR-ZP879 Anti-CD123 (9G52) h(41BB-CD3ζ) CAR, pCDCAR1 Human 9G52 Rat scFv-41BB-CD3ζ Lentiviral vector T cell   Inquiry
  Datasheet
CAR-ZP880 Anti-CD123 (5B11) h(CD28-CD3ζ) CAR, pCDCAR1 Human 5B11 Rat scFv-CD28-CD3ζ Lentiviral vector T cell   Inquiry
  Datasheet
CAR-ZP881 Anti-CD123 (5B11) h(41BB-CD3ζ) CAR, pCDCAR1 Human 5B11 Rat scFv-41BB-CD3ζ Lentiviral vector T cell   Inquiry
  Datasheet
CAR-ZP882 Anti-CD123 (6A367) h(CD28-CD3ζ) CAR, pCDCAR1 Human 6A367 Rat scFv-CD28-CD3ζ Lentiviral vector T cell   Inquiry
  Datasheet
CAR-ZP883 Anti-CD123 (6A367) h(41BB-CD3ζ) CAR, pCDCAR1 Human 6A367 Rat scFv-41BB-CD3ζ Lentiviral vector T cell   Inquiry
  Datasheet
CAR-ZP884 Anti-CD123 (WA63) h(CD28-CD3ζ) CAR, pCDCAR1 Human WA63 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Inquiry
  Datasheet
CAR-ZP885 Anti-CD123 (WA63) h(41BB-CD3ζ) CAR, pCDCAR1 Human WA63 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Inquiry
  Datasheet
CAR-ZP886 Anti-CD123 (AC145) h(CD28-CD3ζ) CAR, pCDCAR1 Human AC145 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Inquiry
  Datasheet
CAR-ZP887 Anti-CD123 (AC145) h(41BB-CD3ζ) CAR, pCDCAR1 Human AC145 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Inquiry
  Datasheet
CAR-ZP888 Anti-CD123 (8E11C5) h(CD28-CD3ζ) CAR, pCDCAR1 Human 8E11C5 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Inquiry
  Datasheet
CAR-ZP899 Anti-CD123 (LAA3) h(41BB-CD3ζ) CAR, pCDCAR1 Human LAA3 Rat scFv-41BB-CD3ζ Lentiviral vector T cell   Inquiry
  Datasheet
CAR-ZP900 Anti-CD123 (LAA4) h(CD28-CD3ζ) CAR, pCDCAR1 Human LAA4 Rat scFv-CD28-CD3ζ Lentiviral vector T cell   Inquiry
  Datasheet
CAR-ZP901 Anti-CD123 (LAA4) h(41BB-CD3ζ) CAR, pCDCAR1 Human LAA4 Rat scFv-41BB-CD3ζ Lentiviral vector T cell   Inquiry
  Datasheet
CAR-ZP902 Anti-CD123 (LAA6) h(CD28-CD3ζ) CAR, pCDCAR1 Human LAA6 Rat scFv-CD28-CD3ζ Lentiviral vector T cell   Inquiry
  Datasheet
CAR-ZP903 Anti-CD123 (LAA6) h(41BB-CD3ζ) CAR, pCDCAR1 Human LAA6 Rat scFv-41BB-CD3ζ Lentiviral vector T cell   Inquiry
  Datasheet
CAR-ZP904 Anti-CD123 (LAA8) h(CD28-CD3ζ) CAR, pCDCAR1 Human LAA8 Rat scFv-CD28-CD3ζ Lentiviral vector T cell   Inquiry
  Datasheet
CAR-ZP905 Anti-CD123 (LAA8) h(41BB-CD3ζ) CAR, pCDCAR1 Human LAA8 Rat scFv-41BB-CD3ζ Lentiviral vector T cell   Inquiry
  Datasheet
CAR-ZP906 Anti-CD123 (LAB11) h(CD28-CD3ζ) CAR, pCDCAR1 Human LAB11 Rat scFv-CD28-CD3ζ Lentiviral vector T cell   Inquiry
  Datasheet
CAR-ZP907 Anti-CD123 (LAB11) h(41BB-CD3ζ) CAR, pCDCAR1 Human LAB11 Rat scFv-41BB-CD3ζ Lentiviral vector T cell   Inquiry
  Datasheet
CAR-ZP908 Anti-CD123 (LAB2) h(CD28-CD3ζ) CAR, pCDCAR1 Human LAB2 Rat scFv-CD28-CD3ζ Lentiviral vector T cell   Inquiry
  Datasheet
CAR-ZP909 Anti-CD123 (LAB2) h(41BB-CD3ζ) CAR, pCDCAR1 Human LAB2 Rat scFv-41BB-CD3ζ Lentiviral vector T cell   Inquiry
  Datasheet
CAR-ZP910 Anti-CD123 (LAC11) h(CD28-CD3ζ) CAR, pCDCAR1 Human LAC11 Rat scFv-CD28-CD3ζ Lentiviral vector T cell   Inquiry
  Datasheet
CAR-ZP911 Anti-CD123 (LAC11) h(41BB-CD3ζ) CAR, pCDCAR1 Human LAC11 Rat scFv-41BB-CD3ζ Lentiviral vector T cell   Inquiry
  Datasheet
CAR-ZP912 Anti-CD123 (LAC12) h(CD28-CD3ζ) CAR, pCDCAR1 Human LAC12 Rat scFv-CD28-CD3ζ Lentiviral vector T cell   Inquiry
  Datasheet
CAR-ZP913 Anti-CD123 (LAC12) h(41BB-CD3ζ) CAR, pCDCAR1 Human LAC12 Rat scFv-41BB-CD3ζ Lentiviral vector T cell   Inquiry
  Datasheet
CAR-ZP914 Anti-CD123 (LAE4) h(CD28-CD3ζ) CAR, pCDCAR1 Human LAE4 Rat scFv-CD28-CD3ζ Lentiviral vector T cell   Inquiry
  Datasheet
CAR-ZP915 Anti-CD123 (LAE4) h(41BB-CD3ζ) CAR, pCDCAR1 Human LAE4 Rat scFv-41BB-CD3ζ Lentiviral vector T cell   Inquiry
  Datasheet
CAR-ZP916 Anti-CD123 (LAF7) h(CD28-CD3ζ) CAR, pCDCAR1 Human LAF7 Rat scFv-CD28-CD3ζ Lentiviral vector T cell   Inquiry
  Datasheet
CAR-ZP917 Anti-CD123 (LAF7) h(41BB-CD3ζ) CAR, pCDCAR1 Human LAF7 Rat scFv-41BB-CD3ζ Lentiviral vector T cell   Inquiry
  Datasheet
CAR-ZP918 Anti-CD123 (LAF5) h(CD28-CD3ζ) CAR, pCDCAR1 Human LAF5 Rat scFv-CD28-CD3ζ Lentiviral vector T cell   Inquiry
  Datasheet
CAR-ZP919 Anti-CD123 (LAF5) h(41BB-CD3ζ) CAR, pCDCAR1 Human LAF5 Rat scFv-41BB-CD3ζ Lentiviral vector T cell   Inquiry
  Datasheet
CAR-ZP920 Anti-CD123 (LAG12) h(CD28-CD3ζ) CAR, pCDCAR1 Human LAG12 Rat scFv-CD28-CD3ζ Lentiviral vector T cell   Inquiry
  Datasheet
CAR-ZP921 Anti-CD123 (LAG12) h(41BB-CD3ζ) CAR, pCDCAR1 Human LAG12 Rat scFv-41BB-CD3ζ Lentiviral vector T cell   Inquiry
  Datasheet
CAR-ZP922 Anti-CD123 (LAH3) h(CD28-CD3ζ) CAR, pCDCAR1 Human LAH3 Rat scFv-CD28-CD3ζ Lentiviral vector T cell   Inquiry
  Datasheet
CAR-ZP923 Anti-CD123 (LAH3) h(41BB-CD3ζ) CAR, pCDCAR1 Human LAH3 Rat scFv-41BB-CD3ζ Lentiviral vector T cell   Inquiry
  Datasheet

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