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EXPLORE MOREMucin 1, cell surface associated (MUC1) or polymorphic epithelial mucin (PEM) is a mucin encoded by the MUC1 gene in humans. MUC1 is a glycoprotein with extensive O-linked glycosylation of its extracellular domain. It is overexpressed in a variety of epithelial cancers, and plays a crucial role in progression of the disease. Tumor-associated MUC1 differs from the MUC1 expressed in normal cells with regard to its biochemical features, cellular distribution, and function. In cancer cells, MUC1 participates in intracellular signal transduction pathways and regulates the expression of its target genes at both the transcriptional and post-transcriptional levels.
Associated Disease
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| CAT | Product Name | Target Species | Antibody Clone | Antibody Host | Receptor Construction | Vector Type | Targeting Cell Type | Inquiry & Datasheet |
| CAR-YF251 | Anti-MUC1 (CBL-YF066) h(4-1BB-CD3ζ) CAR, pCDCAR1 | Human | CBL-YF066 | Humanized | scFv-4-1BB-CD3ζ | Lentiviral vector | T cell | |
| CAR-YF252 | Anti-MUC1 (CBL-YF066) h(CD28-CD3ζ) CAR, pCDCAR1 | Human | CBL-YF066 | Humanized | scFv-CD28-CD3ζ | Lentiviral vector | T cell | |
| CAR-ZP020 | Anti-MUC1h(CD28-CD3ζ) CAR, pCDCAR1 | Human | Mouse | scFv-CD28-CD3ζ | Lentiviral vector | T cell | ||
| CAR-ZP046 | Anti-MUC1h(41BB-CD3ζ) CAR, pCDCAR1 | Human | Mouse | scFv-4-1BB-CD3ζ | Lentiviral vector | T cell | ||
| CAR-ZP8854 | Anti-MUC1 (F1C-HL) h(4-1BB-CD3ζ) CAR, pCDCAR1 | Human | F1C-HL | Human | scFv-4-1BB-CD3ζ | Lentiviral vector | T cell | |
| CAR-0120ZP3407 | Anti-MUC1 (Clivatuzumab) h(CD28-CD3ζ) CAR, pCDCAR1 | Human | Clivatuzumab | Humanized | scFv-CD28-CD3ζ | Lentiviral vector | T Cell | |
| CAR-0120ZP3418 | Anti-MUC1 (SN-102) h(4-1BB-CD3ζ) CAR, pCDCAR1 | Human | SN-102 | Mouse | scFv-4-1BB-CD3ζ | Lentiviral vector | T Cell | |
| CAR-0120ZP3419 | Anti-MUC1 (SN-101) h(CD28-CD3ζ) CAR, pCDCAR1 | Human | SN-101 | Mouse | scFv-CD28-CD3ζ | Lentiviral vector | T Cell | |
| CAR-0120ZP3420 | Anti-MUC1 (SN-101) h(4-1BB-CD3ζ) CAR, pCDCAR1 | Human | SN-101 | Mouse | scFv-4-1BB-CD3ζ | Lentiviral vector | T Cell | |
| CAR-0120ZP3421 | Anti-MUC1 (2D9) h(CD28-CD3ζ) CAR, pCDCAR1 | Human | 2D9 | Mouse | scFv-CD28-CD3ζ | Lentiviral vector | T Cell | |
| CAR-0120ZP3422 | Anti-MUC1 (2D9) h(4-1BB-CD3ζ) CAR, pCDCAR1 | Human | 2D9 | Mouse | scFv-4-1BB-CD3ζ | Lentiviral vector | T Cell | |
| CAR-0120ZP3423 | Anti-MUC1 (014E) h(CD28-CD3ζ) CAR, pCDCAR1 | Human | 014E | Mouse | scFv-CD28-CD3ζ | Lentiviral vector | T Cell | |
| CAR-0120ZP3424 | Anti-MUC1 (014E) h(4-1BB-CD3ζ) CAR, pCDCAR1 | Human | 014E | Mouse | scFv-4-1BB-CD3ζ | Lentiviral vector | T Cell | |
| CAR-0120ZP3425 | Anti-MUC1 (2B11) h(CD28-CD3ζ) CAR, pCDCAR1 | Human | 2B11 | Mouse | scFv-CD28-CD3ζ | Lentiviral vector | T Cell | |
| CAR-0120ZP3426 | Anti-MUC1 (2B11) h(4-1BB-CD3ζ) CAR, pCDCAR1 | Human | 2B11 | Mouse | scFv-4-1BB-CD3ζ | Lentiviral vector | T Cell | |
| CAR-0120ZP3427 | Anti-MUC1 (4G5) h(CD28-CD3ζ) CAR, pCDCAR1 | Human | 4G5 | Mouse | scFv-CD28-CD3ζ | Lentiviral vector | T Cell | |
| CAR-0120ZP3428 | Anti-MUC1 (4G5) h(4-1BB-CD3ζ) CAR, pCDCAR1 | Human | 4G5 | Mouse | scFv-4-1BB-CD3ζ | Lentiviral vector | T Cell | |
| CAR-0120ZP3476 | Anti-MUC1 (SPM132) h(4-1BB-CD3ζ) CAR, pCDCAR1 | Human | SPM132 | Mouse | scFv-4-1BB-CD3ζ | Lentiviral vector | T Cell | |
| CAR-0120ZP3477 | Anti-MUC1 (115D8) h(CD28-CD3ζ) CAR, pCDCAR1 | Human | 115D8 | Mouse | scFv-CD28-CD3ζ | Lentiviral vector | T Cell | |
| CAR-0120ZP3478 | Anti-MUC1 (115D8) h(4-1BB-CD3ζ) CAR, pCDCAR1 | Human | 115D8 | Mouse | scFv-4-1BB-CD3ζ | Lentiviral vector | T Cell | |
| CAR-0120ZP3479 | Anti-MUC1 (VU-5F12) h(CD28-CD3ζ) CAR, pCDCAR1 | Human | VU-5F12 | Mouse | scFv-CD28-CD3ζ | Lentiviral vector | T Cell | |
| CAR-0120ZP3480 | Anti-MUC1 (VU-5F12) h(4-1BB-CD3ζ) CAR, pCDCAR1 | Human | VU-5F12 | Mouse | scFv-4-1BB-CD3ζ | Lentiviral vector | T Cell | |
| CAR-0120ZP3481 | Anti-MUC1 (VU-3D1) h(CD28-CD3ζ) CAR, pCDCAR1 | Human | VU-3D1 | Mouse | scFv-CD28-CD3ζ | Lentiviral vector | T Cell | |
| CAR-0120ZP3482 | Anti-MUC1 (VU-3D1) h(4-1BB-CD3ζ) CAR, pCDCAR1 | Human | VU-3D1 | Mouse | scFv-4-1BB-CD3ζ | Lentiviral vector | T Cell | |
| CAR-0120ZP3483 | Anti-MUC1 (VU-3C6) h(CD28-CD3ζ) CAR, pCDCAR1 | Human | VU-3C6 | Mouse | scFv-CD28-CD3ζ | Lentiviral vector | T Cell | |
| CAR-0120ZP3484 | Anti-MUC1 (VU-3C6) h(4-1BB-CD3ζ) CAR, pCDCAR1 | Human | VU-3C6 | Mouse | scFv-4-1BB-CD3ζ | Lentiviral vector | T Cell | |
| CAR-0120ZP3485 | Anti-MUC1 (SPM492) h(CD28-CD3ζ) CAR, pCDCAR1 | Human | SPM492 | Mouse | scFv-CD28-CD3ζ | Lentiviral vector | T Cell | |
| CAR-0120ZP3486 | Anti-MUC1 (SPM492) h(4-1BB-CD3ζ) CAR, pCDCAR1 | Human | SPM492 | Mouse | scFv-4-1BB-CD3ζ | Lentiviral vector | T Cell | |
| CAR-0120ZP3487 | Anti-MUC1 (S1D12D7) h(CD28-CD3ζ) CAR, pCDCAR1 | Human | S1D12D7 | Mouse | scFv-CD28-CD3ζ | Lentiviral vector | T Cell | |
| CAR-0120ZP3488 | Anti-MUC1 (S1D12D7) h(4-1BB-CD3ζ) CAR, pCDCAR1 | Human | S1D12D7 | Mouse | scFv-4-1BB-CD3ζ | Lentiviral vector | T Cell | |
| CAR-0120ZP3489 | Anti-MUC1 (GP1.4) h(CD28-CD3ζ) CAR, pCDCAR1 | Human | GP1.4 | Mouse | scFv-CD28-CD3ζ | Lentiviral vector | T Cell | |
| CAR-0120ZP3490 | Anti-MUC1 (GP1.4) h(4-1BB-CD3ζ) CAR, pCDCAR1 | Human | GP1.4 | Mouse | scFv-4-1BB-CD3ζ | Lentiviral vector | T Cell | |
| CAR-0120ZP3491 | Anti-MUC1 (G22-L) h(CD28-CD3ζ) CAR, pCDCAR1 | Human | G22-L | Rabbit | scFv-CD28-CD3ζ | Lentiviral vector | T Cell | |
| CAR-0120ZP3492 | Anti-MUC1 (G22-L) h(4-1BB-CD3ζ) CAR, pCDCAR1 | Human | G22-L | Rabbit | scFv-4-1BB-CD3ζ | Lentiviral vector | T Cell | |
| CAR-0120ZP3493 | Anti-MUC1 (E29) h(CD28-CD3ζ) CAR, pCDCAR1 | Human | E29 | Mouse | scFv-CD28-CD3ζ | Lentiviral vector | T Cell | |
| CAR-0120ZP3494 | Anti-MUC1 (E29) h(4-1BB-CD3ζ) CAR, pCDCAR1 | Human | E29 | Mouse | scFv-4-1BB-CD3ζ | Lentiviral vector | T Cell | |
| CAR-0120ZP3495 | Anti-MUC1 (9j112) h(CD28-CD3ζ) CAR, pCDCAR1 | Human | 9j112 | Mouse | scFv-CD28-CD3ζ | Lentiviral vector | T Cell | |
| CAR-0120ZP3496 | Anti-MUC1 (9j112) h(4-1BB-CD3ζ) CAR, pCDCAR1 | Human | 9j112 | Mouse | scFv-4-1BB-CD3ζ | Lentiviral vector | T Cell | |
| CAR-0120ZP3497 | Anti-MUC1 (15B298) h(CD28-CD3ζ) CAR, pCDCAR1 | Human | 15B298 | Mouse | scFv-CD28-CD3ζ | Lentiviral vector | T Cell | |
| CAR-0120ZP3498 | Anti-MUC1 (15B298) h(4-1BB-CD3ζ) CAR, pCDCAR1 | Human | 15B298 | Mouse | scFv-4-1BB-CD3ζ | Lentiviral vector | T Cell |
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