MUC1

Mucin 1, cell surface associated (MUC1) or polymorphic epithelial mucin (PEM) is a mucin encoded by the MUC1 gene in humans. MUC1 is a glycoprotein with extensive O-linked glycosylation of its extracellular domain. It is overexpressed in a variety of epithelial cancers, and plays a crucial role in progression of the disease. Tumor-associated MUC1 differs from the MUC1 expressed in normal cells with regard to its biochemical features, cellular distribution, and function. In cancer cells, MUC1 participates in intracellular signal transduction pathways and regulates the expression of its target genes at both the transcriptional and post-transcriptional levels.

Associated Disease
  • MUC1-expressing tumors, viral infection
  • Others

CAR Vector Products Product list:

Catalog Targeting
Cell Type
Generation Antibody
Clone
Vector
Length
Vector
Type
Vector Design Antibody
Host
Data
sheet
Price
CAR-LC251 T cell Third Pemtumomab ~8kb Nonviral scFv-CD28-41BB-CD3ζ Mouse Inquiry
CAR-LC361 T cell Second Pemtumomab ~8kb Nonviral scFv (MUC1)-CD3ζ/Herin-CD28-41BB Mouse Inquiry
CAR-T-1-M303-2 T cell First SM3; HMFG2 8kb Lentiviral scFv-CD28 Mouse Inquiry
CAR-T-1-M303-G T cell First SM3; HMFG2 8kb Lentiviral scFv-FcεRIγ Mouse Inquiry
CAR-T-1-M303-Z T cell First SM3; HMFG2 8kb Lentiviral scFv-CD3ζ Mouse Inquiry
CAR-T-1-M553-2 T cell First 8kb Lentiviral VHH-CD28 camelid Inquiry
CAR-T-1-M553-G T cell First 8kb Lentiviral VHH-FcεRIγ camelid Inquiry
CAR-T-1-M553-Z T cell First 8kb Lentiviral VHH-CD3ζ camelid Inquiry
CAR-T-2-M303-2G T cell Second SM3; HMFG2 8kb Lentiviral scFv-CD28-FcεRIγ Mouse Inquiry
CAR-T-2-M303-2Z T cell Second SM3; HMFG2 8kb Lentiviral scFv-CD28-CD3ζ Mouse Inquiry
CAR-T-2-M303-4G T cell Second SM3; HMFG2 8kb Lentiviral scFv-CD4-FcεRIγ Mouse Inquiry
CAR-T-2-M303-4Z T cell Second SM3; HMFG2 8kb Lentiviral scFv-CD4-CD3ζ Mouse Inquiry
CAR-T-2-M303-8Z T cell Second SM3; HMFG2 8kb Lentiviral scFv-CD8-CD3ζ Mouse Inquiry
CAR-T-2-M303-BZ T cell Second SM3; HMFG2 8kb Lentiviral scFv-41BB-CD3ζ Mouse Inquiry
CAR-T-2-M303-CZ T cell Second SM3; HMFG2 8kb Lentiviral scFv-b2c-CD3ζ Mouse Inquiry
CAR-T-2-M553-2G T cell Second 8kb Lentiviral VHH-CD28-FcεRIγ camelid Inquiry
CAR-T-2-M553-2Z T cell Second 8kb Lentiviral VHH-CD28-CD3ζ camelid Inquiry
CAR-T-2-M553-4G T cell Second 8kb Lentiviral VHH-CD4-FcεRIγ camelid Inquiry
CAR-T-2-M553-4Z T cell Second 8kb Lentiviral VHH-CD4-CD3ζ camelid Inquiry
CAR-T-2-M553-8Z T cell Second 8kb Lentiviral VHH-CD8-CD3ζ camelid Inquiry
CAR-T-2-M553-BZ T cell Second 8kb Lentiviral VHH-41BB-CD3ζ camelid Inquiry
CAR-T-2-M553-CZ T cell Second 8kb Lentiviral VHH-b2c-CD3ζ camelid Inquiry
CAR-T-3-M303-2BZ T cell Third SM3; HMFG2 8kb Lentiviral scFv-CD28-41BB-CD3ζ Mouse Inquiry
CAR-T-3-M303-2XZ T cell Third SM3; HMFG2 8kb Lentiviral scFv-CD28-OX40-CD3ζ Mouse Inquiry
CAR-T-3-M553-2BZ T cell Third 8kb Lentiviral VHH-CD28-41BB-CD3ζ camelid Inquiry
CAR-T-3-M553-2XZ T cell Third 8kb Lentiviral VHH-CD28-OX40-CD3ζ camelid Inquiry

CAR Viral Particles Product list:

Catalog Antibody
Clone
Packaging
System
Generation Gene
Construct
Promotor Packaging
Cell
Titer Data
sheet
Price
VP-CAR-LC365 SM3 Lentivirus First scFv (SM3)-CD28 CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC366 SM3 Lentivirus First scFv (SM3)-FcεRIγ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC367 SM3 Lentivirus First scFv (SM3)-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC368 SM3 Lentivirus Second scFv (SM3)-CD28-FcεRIγ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC369 SM3 Lentivirus Second scFv (SM3)-CD28-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC370 SM3 Lentivirus Second scFv (SM3)-CD4-FcεRIγ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC371 SM3 Lentivirus Second scFv (SM3)-CD4-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC372 SM3 Lentivirus Second scFv (SM3)-CD8-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC373 SM3 Lentivirus Second scFv (SM3)-41BB-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC374 SM3 Lentivirus Second scFv (SM3)-b2c-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC375 SM3 Lentivirus Third scFv (SM3)-CD28-41BB-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC376 SM3 Lentivirus Third scFv (SM3)-CD28-OX40-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC377 HMFG2 Lentivirus First scFv (HMFG2)-CD28 CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC378 HMFG2 Lentivirus First scFv (HMFG2)-FcεRIγ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC379 HMFG2 Lentivirus First scFv (HMFG2)-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC380 HMFG2 Lentivirus Second scFv (HMFG2)-CD28-FcεRIγ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC381 HMFG2 Lentivirus Second scFv (HMFG2)-CD28-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC382 HMFG2 Lentivirus Second scFv (HMFG2)-CD4-FcεRIγ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC383 HMFG2 Lentivirus Second scFv (HMFG2)-CD4-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC384 HMFG2 Lentivirus Second scFv (HMFG2)-CD8-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC385 HMFG2 Lentivirus Second scFv (HMFG2)-41BB-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC386 HMFG2 Lentivirus Second scFv (HMFG2)-b2c-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC387 HMFG2 Lentivirus Third scFv (HMFG2)-CD28-41BB-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC388 HMFG2 Lentivirus Third scFv (HMFG2)-CD28-OX40-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC723 Lentivirus Second scFv-CD28-41BB-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
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Tel: 1-631-871-5806
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Email:

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Tel: 44-207-048-3343

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