Anti-MUC1 CAR Products - Creative Biolabs

MUC1

Mucin 1, cell surface associated (MUC1) or polymorphic epithelial mucin (PEM) is a mucin encoded by the MUC1 gene in humans. MUC1 is a glycoprotein with extensive O-linked glycosylation of its extracellular domain. It is overexpressed in a variety of epithelial cancers, and plays a crucial role in progression of the disease. Tumor-associated MUC1 differs from the MUC1 expressed in normal cells with regard to its biochemical features, cellular distribution, and function. In cancer cells, MUC1 participates in intracellular signal transduction pathways and regulates the expression of its target genes at both the transcriptional and post-transcriptional levels.

Associated Disease

MUC1-expressing tumors, viral infection
Others

Vector Products
Viral Particles

CAR Vector Products Product list:

Catalog	Targeting Cell Type	Generation	Antibody Clone	Vector Length	Vector Type	Vector Design	Antibody Host	Data sheet	Price
CAR-LC251	T cell	Third	Pemtumomab	~8kb	Nonviral	scFv-CD28-41BB-CD3ζ	Mouse		Inquiry
CAR-LC361	T cell	Second	Pemtumomab	~8kb	Nonviral	scFv (MUC1)-CD3ζ/Herin-CD28-41BB	Mouse		Inquiry
CAR-T-1-M303-2	T cell	First	SM3; HMFG2	8kb	Lentiviral	scFv-CD28	Mouse		Inquiry
CAR-T-1-M303-G	T cell	First	SM3; HMFG2	8kb	Lentiviral	scFv-FcεRIγ	Mouse		Inquiry
CAR-T-1-M303-Z	T cell	First	SM3; HMFG2	8kb	Lentiviral	scFv-CD3ζ	Mouse		Inquiry
CAR-T-1-M553-2	T cell	First		8kb	Lentiviral	VHH-CD28	camelid		Inquiry
CAR-T-1-M553-G	T cell	First		8kb	Lentiviral	VHH-FcεRIγ	camelid		Inquiry
CAR-T-1-M553-Z	T cell	First		8kb	Lentiviral	VHH-CD3ζ	camelid		Inquiry
CAR-T-2-M303-2G	T cell	Second	SM3; HMFG2	8kb	Lentiviral	scFv-CD28-FcεRIγ	Mouse		Inquiry
CAR-T-2-M303-2Z	T cell	Second	SM3; HMFG2	8kb	Lentiviral	scFv-CD28-CD3ζ	Mouse		Inquiry
CAR-T-2-M303-4G	T cell	Second	SM3; HMFG2	8kb	Lentiviral	scFv-CD4-FcεRIγ	Mouse		Inquiry
CAR-T-2-M303-4Z	T cell	Second	SM3; HMFG2	8kb	Lentiviral	scFv-CD4-CD3ζ	Mouse		Inquiry
CAR-T-2-M303-8Z	T cell	Second	SM3; HMFG2	8kb	Lentiviral	scFv-CD8-CD3ζ	Mouse		Inquiry
CAR-T-2-M303-BZ	T cell	Second	SM3; HMFG2	8kb	Lentiviral	scFv-41BB-CD3ζ	Mouse		Inquiry
CAR-T-2-M303-CZ	T cell	Second	SM3; HMFG2	8kb	Lentiviral	scFv-b2c-CD3ζ	Mouse		Inquiry
CAR-T-2-M553-2G	T cell	Second		8kb	Lentiviral	VHH-CD28-FcεRIγ	camelid		Inquiry
CAR-T-2-M553-2Z	T cell	Second		8kb	Lentiviral	VHH-CD28-CD3ζ	camelid		Inquiry
CAR-T-2-M553-4G	T cell	Second		8kb	Lentiviral	VHH-CD4-FcεRIγ	camelid		Inquiry
CAR-T-2-M553-4Z	T cell	Second		8kb	Lentiviral	VHH-CD4-CD3ζ	camelid		Inquiry
CAR-T-2-M553-8Z	T cell	Second		8kb	Lentiviral	VHH-CD8-CD3ζ	camelid		Inquiry
CAR-T-2-M553-BZ	T cell	Second		8kb	Lentiviral	VHH-41BB-CD3ζ	camelid		Inquiry
CAR-T-2-M553-CZ	T cell	Second		8kb	Lentiviral	VHH-b2c-CD3ζ	camelid		Inquiry
CAR-T-3-M303-2BZ	T cell	Third	SM3; HMFG2	8kb	Lentiviral	scFv-CD28-41BB-CD3ζ	Mouse		Inquiry
CAR-T-3-M303-2XZ	T cell	Third	SM3; HMFG2	8kb	Lentiviral	scFv-CD28-OX40-CD3ζ	Mouse		Inquiry
CAR-T-3-M553-2BZ	T cell	Third		8kb	Lentiviral	VHH-CD28-41BB-CD3ζ	camelid		Inquiry
CAR-T-3-M553-2XZ	T cell	Third		8kb	Lentiviral	VHH-CD28-OX40-CD3ζ	camelid		Inquiry

CAR Viral Particles Product list:

Catalog	Antibody Clone	Packaging System	Generation	Gene Construct	Promotor	Packaging Cell	Titer	Data sheet	Price
VP-CAR-LC365	SM3	Lentivirus	First	scFv (SM3)-CD28	CMV	293T	> 10⁷ IFU/ml		Inquiry
VP-CAR-LC366	SM3	Lentivirus	First	scFv (SM3)-FcεRIγ	CMV	293T	> 10⁷ IFU/ml		Inquiry
VP-CAR-LC367	SM3	Lentivirus	First	scFv (SM3)-CD3ζ	CMV	293T	> 10⁷ IFU/ml		Inquiry
VP-CAR-LC368	SM3	Lentivirus	Second	scFv (SM3)-CD28-FcεRIγ	CMV	293T	> 10⁷ IFU/ml		Inquiry
VP-CAR-LC369	SM3	Lentivirus	Second	scFv (SM3)-CD28-CD3ζ	CMV	293T	> 10⁷ IFU/ml		Inquiry
VP-CAR-LC370	SM3	Lentivirus	Second	scFv (SM3)-CD4-FcεRIγ	CMV	293T	> 10⁷ IFU/ml		Inquiry
VP-CAR-LC371	SM3	Lentivirus	Second	scFv (SM3)-CD4-CD3ζ	CMV	293T	> 10⁷ IFU/ml		Inquiry
VP-CAR-LC372	SM3	Lentivirus	Second	scFv (SM3)-CD8-CD3ζ	CMV	293T	> 10⁷ IFU/ml		Inquiry
VP-CAR-LC373	SM3	Lentivirus	Second	scFv (SM3)-41BB-CD3ζ	CMV	293T	> 10⁷ IFU/ml		Inquiry
VP-CAR-LC374	SM3	Lentivirus	Second	scFv (SM3)-b2c-CD3ζ	CMV	293T	> 10⁷ IFU/ml		Inquiry
VP-CAR-LC375	SM3	Lentivirus	Third	scFv (SM3)-CD28-41BB-CD3ζ	CMV	293T	> 10⁷ IFU/ml		Inquiry
VP-CAR-LC376	SM3	Lentivirus	Third	scFv (SM3)-CD28-OX40-CD3ζ	CMV	293T	> 10⁷ IFU/ml		Inquiry
VP-CAR-LC377	HMFG2	Lentivirus	First	scFv (HMFG2)-CD28	CMV	293T	> 10⁷ IFU/ml		Inquiry
VP-CAR-LC378	HMFG2	Lentivirus	First	scFv (HMFG2)-FcεRIγ	CMV	293T	> 10⁷ IFU/ml		Inquiry
VP-CAR-LC379	HMFG2	Lentivirus	First	scFv (HMFG2)-CD3ζ	CMV	293T	> 10⁷ IFU/ml		Inquiry
VP-CAR-LC380	HMFG2	Lentivirus	Second	scFv (HMFG2)-CD28-FcεRIγ	CMV	293T	> 10⁷ IFU/ml		Inquiry
VP-CAR-LC381	HMFG2	Lentivirus	Second	scFv (HMFG2)-CD28-CD3ζ	CMV	293T	> 10⁷ IFU/ml		Inquiry
VP-CAR-LC382	HMFG2	Lentivirus	Second	scFv (HMFG2)-CD4-FcεRIγ	CMV	293T	> 10⁷ IFU/ml		Inquiry
VP-CAR-LC383	HMFG2	Lentivirus	Second	scFv (HMFG2)-CD4-CD3ζ	CMV	293T	> 10⁷ IFU/ml		Inquiry
VP-CAR-LC384	HMFG2	Lentivirus	Second	scFv (HMFG2)-CD8-CD3ζ	CMV	293T	> 10⁷ IFU/ml		Inquiry
VP-CAR-LC385	HMFG2	Lentivirus	Second	scFv (HMFG2)-41BB-CD3ζ	CMV	293T	> 10⁷ IFU/ml		Inquiry
VP-CAR-LC386	HMFG2	Lentivirus	Second	scFv (HMFG2)-b2c-CD3ζ	CMV	293T	> 10⁷ IFU/ml		Inquiry
VP-CAR-LC387	HMFG2	Lentivirus	Third	scFv (HMFG2)-CD28-41BB-CD3ζ	CMV	293T	> 10⁷ IFU/ml		Inquiry
VP-CAR-LC388	HMFG2	Lentivirus	Third	scFv (HMFG2)-CD28-OX40-CD3ζ	CMV	293T	> 10⁷ IFU/ml		Inquiry
VP-CAR-LC723		Lentivirus	Second	scFv-CD28-41BB-CD3ζ	CMV	293T	> 10⁷ IFU/ml		Inquiry

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