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EXPLORE MORECreative Biolabs has a tradition of commitment. To achieve efficient execution and regulatory approval, we offer careful considerations of your program for the development of a cellular or gene therapy product – now and in the future.
EXPLORE MOREWe focus on unmet needs and develop novel cellular and gene drugs and solutions that offer significant benefits over existing options.
EXPLORE MORETo accelerate advanced breakthroughs of your projects, we offer broad range of platforms which enable our clients be free to tackle problems with cutting-edge technologies from different angles and in different methods.
EXPLORE MOREUse the resources in our library to help you understand your options and make critical decisions for your study. We offer oncolytic virus, CAR-T, and dendritic cell related documents, as well as newsletter. If you don’t find the answers you’re looking for, contact us for additional assistance.
EXPLORE MOREMucin 1, cell surface associated (MUC1) or polymorphic epithelial mucin (PEM) is a mucin encoded by the MUC1 gene in humans. MUC1 is a glycoprotein with extensive O-linked glycosylation of its extracellular domain. It is overexpressed in a variety of epithelial cancers, and plays a crucial role in progression of the disease. Tumor-associated MUC1 differs from the MUC1 expressed in normal cells with regard to its biochemical features, cellular distribution, and function. In cancer cells, MUC1 participates in intracellular signal transduction pathways and regulates the expression of its target genes at both the transcriptional and post-transcriptional levels.
Associated Disease
Loading...| CAT | Product Name | Target Species | Antibody Clone | Antibody Host | Receptor Construction | Vector Type | Targeting Cell Type | Inquiry & Datasheet |
| CAR-T-1-M303-2 | Anti-MUC1 scFv h(CD28) CART, pCDCAR1 | Human | SM3; HMFG2 | Mouse | scFv-CD28 | Lentiviral | T cell | |
| CAR-T-1-M303-G | Anti-MUC1 scFv h(FcεRIγ) CART, pCDCAR1 | Human | SM3; HMFG2 | Mouse | scFv-FcεRIγ | Lentiviral | T cell | |
| CAR-T-1-M303-Z | Anti-MUC1 scFv h(CD3ζ) CART, pCDCAR1 | Human | SM3; HMFG2 | Mouse | scFv-CD3ζ | Lentiviral | T cell | |
| CAR-T-2-M303-2G | Anti-MUC1 scFv h(CD28-FcεRIγ) CART, pCDCAR1 | Human | SM3; HMFG2 | Mouse | scFv-CD28-FcεRIγ | Lentiviral | T cell | |
| CAR-T-2-M303-2Z | Anti-MUC1 scFv h(CD28-CD3ζ) CART, pCDCAR1 | Human | SM3; HMFG2 | Mouse | scFv-CD28-CD3ζ | Lentiviral | T cell | |
| CAR-T-2-M303-4G | Anti-MUC1 scFv h(CD4-FcεRIγ) CART, pCDCAR1 | Human | SM3; HMFG2 | Mouse | scFv-CD4-FcεRIγ | Lentiviral | T cell | |
| CAR-T-2-M303-4Z | Anti-MUC1 scFv h(CD4-CD3ζ) CART, pCDCAR1 | Human | SM3; HMFG2 | Mouse | scFv-CD4-CD3ζ | Lentiviral | T cell | |
| CAR-T-2-M303-8Z | Anti-MUC1 scFv h(CD8-CD3ζ) CART, pCDCAR1 | Human | SM3; HMFG2 | Mouse | scFv-CD8-CD3ζ | Lentiviral | T cell | |
| CAR-T-2-M303-BZ | Anti-MUC1 scFv h(41BB-CD3ζ) CART, pCDCAR1 | Human | SM3; HMFG2 | Mouse | scFv-41BB-CD3ζ | Lentiviral | T cell | |
| CAR-T-2-M303-CZ | Anti-MUC1 scFv h(b2c-CD3ζ) CART, pCDCAR1 | Human | SM3; HMFG2 | Mouse | scFv-b2c-CD3ζ | Lentiviral | T cell | |
| CAR-T-3-M303-2BZ | Anti-MUC1 scFv h(CD28-41BB-CD3ζ) CART, pCDCAR1 | Human | SM3; HMFG2 | Mouse | scFv-CD28-41BB-CD3ζ | Lentiviral | T cell | |
| CAR-T-3-M303-2XZ | Anti-MUC1 scFv h(CD28-OX40-CD3ζ) CART, pCDCAR1 | Human | SM3; HMFG2 | Mouse | scFv-CD28-OX40-CD3ζ | Lentiviral | T cell | |
| CAR-T-2-M553-BZ | Anti-MUC1 VHH h(41BB-CD3ζ) CAR, [T] | Human | camelid | VHH-41BB-CD3ζ | Lentiviral | T cell | ||
| CAR-T-2-M553-CZ | Anti-MUC1 VHH h(b2c-CD3ζ) CAR, [T] | Human | camelid | VHH-b2c-CD3ζ | Lentiviral | T cell | ||
| CAR-T-1-M553-2 | Anti-MUC1 VHH h(CD28) CAR, [T] | Human | camelid | VHH-CD28 | Lentiviral | T cell | ||
| CAR-T-3-M553-2BZ | Anti-MUC1 VHH h(CD28-41BB-CD3ζ) CAR, [T] | Human | camelid | VHH-CD28-41BB-CD3ζ | Lentiviral | T cell | ||
| CAR-T-2-M553-2Z | Anti-MUC1 VHH h(CD28-CD3ζ) CAR, [T] | Human | camelid | VHH-CD28-CD3ζ | Lentiviral | T cell | ||
| CAR-T-2-M553-2G | Anti-MUC1 VHH h(CD28-FcεRIγ) CAR, [T] | Human | camelid | VHH-CD28-FcεRIγ | Lentiviral | T cell | ||
| CAR-T-3-M553-2XZ | Anti-MUC1 VHH h(CD28-OX40-CD3ζ) CAR, [T] | Human | camelid | VHH-CD28-OX40-CD3ζ | Lentiviral | T cell | ||
| CAR-T-1-M553-Z | Anti-MUC1 VHH h(CD3ζ) CAR, [T] | Human | camelid | VHH-CD3ζ | Lentiviral | T cell | ||
| CAR-T-2-M553-4Z | Anti-MUC1 VHH h(CD4-CD3ζ) CAR, [T] | Human | camelid | VHH-CD4-CD3ζ | Lentiviral | T cell | ||
| CAR-T-2-M553-4G | Anti-MUC1 VHH h(CD4-FcεRIγ) CAR, [T] | Human | camelid | VHH-CD4-FcεRIγ | Lentiviral | T cell | ||
| CAR-T-2-M553-8Z | Anti-MUC1 VHH h(CD8-CD3ζ) CAR, [T] | Human | camelid | VHH-CD8-CD3ζ | Lentiviral | T cell | ||
| CAR-T-1-M553-G | Anti-MUC1 VHH h(FcεRIγ) CAR, [T] | Human | camelid | VHH-FcεRIγ | Lentiviral | T cell | ||
| CAR-LC251 | Anti-MUC1 h(CD28-41BB-CD3ζ) CAR, pCDCAR1 | Human | Pemtumomab | Mouse | scFv-CD28-41BB-CD3ζ | Nonviral | T cell | |
| CAR-LC361 | Anti-MUC1×ERBB2 h(CD3ζ/41BB) Dual CAR, pCDCAR1 | Human | Pemtumomab | Mouse | scFv (MUC1)-CD3ζ/Herin-CD28-41BB | Nonviral | T cell | |
| CAR-CQ1611 | Anti-MUC1 (CBXC-0851) h(41BB-CD3ζ) CAR, pCDCAR1 | Human | CBXC-0851 | Human | scFv-41BB-CD3ζ | Lentiviral vector | T cell | |
| CAR-CQ5035 | Anti-MUC1 (CBXC-0851) h(CD28-CD3ζ) CAR, pCDCAR1 | Human | CBXC-0851 | Human | scFv-CD28-CD3ζ | Lentiviral vector | T cell | |
| CAR-WFY0609 | Anti-MUC1 (126E7) h(41BB-CD3ζ) CAR, pCDCAR1 | Human | 126E7 | Mouse | scFv-41BB-CD3ζ | Lentiviral vector | T cell | |
| CAR-WFY0610 | Anti-MUC1 (139H2) h(41BB-CD3ζ) CAR, pCDCAR1 | Human | 139H2 | Mouse | scFv-41BB-CD3ζ | Lentiviral vector | T cell | |
| CAR-WFY0611 | Anti-MUC1 (C595NCRC48) h(41BB-CD3ζ) CAR, pCDCAR1 | Human | C595NCRC48 | Mouse | scFv-41BB-CD3ζ | Lentiviral vector | T cell | |
| CAR-YF251 | Anti-MUC1 (CBL-YF066) h(4-1BB-CD3ζ) CAR, pCDCAR1 | Human | CBL-YF066 | Humanized | scFv-4-1BB-CD3ζ | Lentiviral vector | T cell | |
| CAR-YF252 | Anti-MUC1 (CBL-YF066) h(CD28-CD3ζ) CAR, pCDCAR1 | Human | CBL-YF066 | Humanized | scFv-CD28-CD3ζ | Lentiviral vector | T cell | |
| CAR-ZP020 | Anti-MUC1h(CD28-CD3ζ) CAR, pCDCAR1 | Human | Mouse | scFv-CD28-CD3ζ | Lentiviral vector | T cell | ||
| CAR-ZP046 | Anti-MUC1h(41BB-CD3ζ) CAR, pCDCAR1 | Human | Mouse | scFv-4-1BB-CD3ζ | Lentiviral vector | T cell | ||
| CAR-ZP8854 | Anti-MUC1 (F1C-HL) h(4-1BB-CD3ζ) CAR, pCDCAR1 | Human | F1C-HL | Human | scFv-4-1BB-CD3ζ | Lentiviral vector | T cell | |
| CAR-ZP8855 | Anti-MUC1 (M1A-HL) h(CD28-CD3ζ) CAR, pCDCAR1 | Human | M1A-HL | Human | scFv-CD28-CD3ζ | Lentiviral vector | T cell | |
| CAR-ZP8856 | Anti-MUC1 (M1A-HL) h(4-1BB-CD3ζ) CAR, pCDCAR1 | Human | M1A-HL | Human | scFv-4-1BB-CD3ζ | Lentiviral vector | T cell | |
| CAR-ZP8857 | Anti-MUC1 (K2B-HL) h(CD28-CD3ζ) CAR, pCDCAR1 | Human | K2B-HL | Human | scFv-CD28-CD3ζ | Lentiviral vector | T cell | |
| CAR-ZP8858 | Anti-MUC1 (K2B-HL) h(4-1BB-CD3ζ) CAR, pCDCAR1 | Human | K2B-HL | Human | scFv-4-1BB-CD3ζ | Lentiviral vector | T cell |
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