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APC-labeled Human MUC1 CAR Detection Reagent, His Tag (XS-0923-LX19)


All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

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Specifications

  • Target
  • MUC1
  • Organism
  • Human
  • Application
  • Used for evaluating CAR expression.
  • Purity
  • >90%
  • Endotoxin Level
  • Less than 1.0 EU per μg by the LAL method.
  • Storage
  • For long term storage, the product should be stored at lyophilized state at -20°C or lower.
    Please protect from light and avoid repeated freeze-thaw cycles.
  • Shelf-Life
  • Stable as supplied until expiry date on label.
  • Application Notes
  • This product is recommended for FC application, and the optimal working dilutions should be determined by the end user.
  • Diseases
  • Seminal vesicle cancer
  • Molecular Characterization
  • It contains AA Ser 33 - Gly 167 (Accession # AAI20976).
  • Conjugation
  • APC
  • Size
  • 25 tests; 100 tests
  • Formulation
  • Lyophilized from 0.22 μm filtered solution in 50 mM Tris, 100 mM Glycine, pH7.5. Normally trehalose is added as protectant before lyophilization.
  • Expression
  • Human HEK293 cells
  • Host Species
  • Human
  • Species Reactivity
  • Human
  • Form
  • Lyophilized

Target

  • Target Introduction
  • Mucin-1 (MUC1) is also known as Tumor-associated epithelial membrane antigen (EMA), Polymorphic epithelial mucin (PEM), Peanut-reactive urinary mucin (PUM), PEMT, Krebs von den Lungen-6 (KL-6), CD antigen CD227, Episialin, H23AG. MUC1 is a glycoprotein with extensive O-linked glycosylation of its extracellular domain. Mucins line the apical surface of epithelial cells in the lungs, stomach, intestines, eyes and several other organs. Mucins protect the body from infection by pathogen binding to oligosaccharides in the extracellular domain, preventing the pathogen from reaching the cell surface. Except protective function by binding to pathogens, MUC1 also functions in a cell signaling capacity. Overexpression of MUC1 is often associated with colon, breast, ovarian, lung and pancreatic cancers.
  • Target Alternative Names
  • Mucin 1
  • Entrez Gene ID
  • 4982

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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