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Mesothelin

Mesothelin also called MSLN is encoded by MSLN, which is a tumor differentiation antigen that is normally present on the mesothelial cells lining the pleura, peritoneum and pericardium. The limited mesothelin expression in normal tissues and high expression in many cancers makes it an attractive candidate for therapy. Mesothelin not only is related to mesothelioma, ovarian cancer, pancreatic cancer and lung cancer but also is associated with squamous cell carcinomas such as cervix, lung and head and neck carcinomas and adenocarcinomas.

Associated Disease
  • CAR Vector Products
  • TCR Vector Products
  • CAR Viral Particles
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CAT Product Name Target SpeciesAntibody CloneAntibody HostReceptor ConstructionVector TypeTargeting Cell Type Inquiry & Datasheet
CAR-T-1-M321-2 Anti-mesothelin scFv h(CD28) CART, pCDCAR1 Human SS1 Mouse scFv-CD28 Lentiviral T cell   Inquiry
  Datasheet
CAR-T-1-M321-G Anti-mesothelin scFv h(FcεRIγ) CART, pCDCAR1 Human SS1 Mouse scFv-FcεRIγ Lentiviral T cell   Inquiry
  Datasheet
CAR-T-1-M321-Z Anti-mesothelin scFv h(CD3ζ) CART, pCDCAR1 Human SS1 Mouse scFv-CD3ζ Lentiviral T cell   Inquiry
  Datasheet
CAR-T-2-M321-2G Anti-mesothelin scFv h(CD28-FcεRIγ) CART, pCDCAR1 Human SS1 Mouse scFv-CD28-FcεRIγ Lentiviral T cell   Inquiry
  Datasheet
CAR-T-2-M321-2Z Anti-mesothelin scFv h(CD28-CD3ζ) CART, pCDCAR1 Human SS1 Mouse scFv-CD28-CD3ζ Lentiviral T cell   Inquiry
  Datasheet
CAR-T-2-M321-4G Anti-mesothelin scFv h(CD4-FcεRIγ) CART, pCDCAR1 Human SS1 Mouse scFv-CD4-FcεRIγ Lentiviral T cell   Inquiry
  Datasheet
CAR-T-2-M321-8Z Anti-mesothelin scFv h(CD8-CD3ζ) CART, pCDCAR1 Human SS1 Mouse scFv-CD8-CD3ζ Lentiviral T cell   Inquiry
  Datasheet
CAR-T-2-M321-BZ Anti-mesothelin scFv h(41BB-CD3ζ) CART, pCDCAR1 Human SS1 Mouse scFv-41BB-CD3ζ Lentiviral T cell   Inquiry
  Datasheet
CAR-T-2-M321-CZ Anti-mesothelin scFv h(b2c-CD3ζ) CART, pCDCAR1 Human SS1 Mouse scFv-b2c-CD3ζ Lentiviral T cell   Inquiry
  Datasheet
CAR-T-3-M321-2BZ Anti-mesothelin scFv h(CD28-41BB-CD3ζ) CART, pCDCAR1 Human SS1 Mouse scFv-CD28-41BB-CD3ζ Lentiviral T cell   Inquiry
  Datasheet
CAR-LC023 Anti-Mesothelin (m912) h(CD3ζ) CAR, pCDCAR1 Human m912 Human scFv-CD3ζ Retroviral T cell   Inquiry
  Datasheet
CAR-LC024 Anti-Mesothelin (m912) h(CD28-CD3ζ) CAR, pCDCAR1 Human m912 Human scFv-CD28-CD3ζ Retroviral T cell   Inquiry
  Datasheet
CAR-T-3-M321-2XZ Anti-mesothelin scFv h(CD28-OX40-CD3ζ) CART, pCDCAR1 Human SS1 Mouse scFv-CD28-OX40-CD3ζ Lentiviral T cell   Inquiry
  Datasheet
CAR-LC037 Anti-Mesothelin (SS1) h(ICOS-CD3ζ) CAR, pCDCAR1 Human SS1 Mouse scFv-ICOS-CD3ζ Lentiviral T cell   Inquiry
  Datasheet
CAR-LC053 Anti-Mesothelin (HN1) h(CD28-CD3ζ) CAR, pCDCAR1 Human HN1 Human scFv-CD28-CD3ζ Retroviral T cell   Inquiry
  Datasheet
CAR-LC054 Anti-Mesothelin (HN1) h(CD28-41BB-CD3ζ) CAR, pCDCAR1 Human HN1 Human scFv-CD28-41BB-CD3ζ Retroviral T cell   Inquiry
  Datasheet
CAR-LC176 Anti-Mesothelin (P4) h(CD3ζ) CAR, pCDCAR1 Human P4 Human scFv-CD3ζ Lentiviral T cell   Inquiry
  Datasheet
CAR-LC177 Anti-Mesothelin (P4) h(CD28-CD3ζ) CAR, pCDCAR1 Human P4 Human scFv-CD28-CD3ζ Lentiviral T cell   Inquiry
  Datasheet
CAR-LC066 Anti-Mesothelin (M1) h(41BB-CD3ζ) CAR, pCDCAR1 Human M1 Human scFv-41BB-CD3ζ Lentiviral T cell   Inquiry
  Datasheet
CAR-LC067 Anti-Mesothelin (M2) h(41BB-CD3ζ) CAR, pCDCAR1 Human M2 Human scFv-41BB-CD3ζ Lentiviral T cell   Inquiry
  Datasheet
CAR-LC089 Anti-Mesothelin (M24) h(41BB-CD3ζ) CAR, pCDCAR1 Human M24 Human scFv-41BB-CD3ζ Lentiviral T cell   Inquiry
  Datasheet
CAR-LC268 Anti-MSLN (HN1) h(41BB/CD3ζ, FKBP/FRB) Conditional CAR, pCDCAR1 Human HN1 Human scFv-41BB-FKBP/41BB-FRB-CD3ζ Lentiviral T cell   Inquiry
  Datasheet
CAR-LC068 Anti-Mesothelin (M3) h(41BB-CD3ζ) CAR, pCDCAR1 Human M3 Human scFv-41BB-CD3ζ Lentiviral T cell   Inquiry
  Datasheet
CAR-LC069 Anti-Mesothelin (M4) h(41BB-CD3ζ) CAR, pCDCAR1 Human M4 Human scFv-41BB-CD3ζ Lentiviral T cell   Inquiry
  Datasheet
CAR-LC070 Anti-Mesothelin (M5) h(41BB-CD3ζ) CAR, pCDCAR1 Human M5 Human scFv-41BB-CD3ζ Lentiviral T cell   Inquiry
  Datasheet
CAR-LC071 Anti-Mesothelin (M6) h(41BB-CD3ζ) CAR, pCDCAR1 Human M6 Human scFv-41BB-CD3ζ Lentiviral T cell   Inquiry
  Datasheet
CAR-LC072 Anti-Mesothelin (M7) h(41BB-CD3ζ) CAR, pCDCAR1 Human M7 Human scFv-41BB-CD3ζ Lentiviral T cell   Inquiry
  Datasheet
CAR-LC073 Anti-Mesothelin (M8) h(41BB-CD3ζ) CAR, pCDCAR1 Human M8 Human scFv-41BB-CD3ζ Lentiviral T cell   Inquiry
  Datasheet
CAR-LC269 Anti-MSLN (SS1) h(41BB/CD3ζ, FKBP/FRB) Conditional CAR, pCDCAR1 Human SS1 Mouse scFv-41BB-FKBP/41BB-FRB-CD3ζ Lentiviral T cell   Inquiry
  Datasheet
CAR-LC270 Anti-MSLN (m912) h(41BB/CD3ζ, FKBP/FRB) Conditional CAR, pCDCAR1 Human m912 Human scFv-41BB-FKBP/41BB-FRB-CD3ζ Lentiviral T cell   Inquiry
  Datasheet
CAR-LC074 Anti-Mesothelin (M9) h(41BB-CD3ζ) CAR, pCDCAR1 Human M9 Human scFv-41BB-CD3ζ Lentiviral T cell   Inquiry
  Datasheet
CAR-LC075 Anti-Mesothelin (M10) h(41BB-CD3ζ) CAR, pCDCAR1 Human M10 Human scFv-41BB-CD3ζ Lentiviral T cell   Inquiry
  Datasheet
CAR-LC076 Anti-Mesothelin (M11) h(41BB-CD3ζ) CAR, pCDCAR1 Human M11 Human scFv-41BB-CD3ζ Lentiviral T cell   Inquiry
  Datasheet
CAR-LC077 Anti-Mesothelin (M12) h(41BB-CD3ζ) CAR, pCDCAR1 Human M12 Human scFv-41BB-CD3ζ Lentiviral T cell   Inquiry
  Datasheet
CAR-LC078 Anti-Mesothelin (M13) h(41BB-CD3ζ) CAR, pCDCAR1 Human M13 Human scFv-41BB-CD3ζ Lentiviral T cell   Inquiry
  Datasheet
CAR-LC079 Anti-Mesothelin (M14) h(41BB-CD3ζ) CAR, pCDCAR1 Human M14 Human scFv-41BB-CD3ζ Lentiviral T cell   Inquiry
  Datasheet
CAR-LC080 Anti-Mesothelin (M15) h(41BB-CD3ζ) CAR, pCDCAR1 Human M15 Human scFv-41BB-CD3ζ Lentiviral T cell   Inquiry
  Datasheet
CAR-LC081 Anti-Mesothelin (M16) h(41BB-CD3ζ) CAR, pCDCAR1 Human M16 Human scFv-41BB-CD3ζ Lentiviral T cell   Inquiry
  Datasheet
CAR-LC082 Anti-Mesothelin (M17) h(41BB-CD3ζ) CAR, pCDCAR1 Human M17 Human scFv-41BB-CD3ζ Lentiviral T cell   Inquiry
  Datasheet
CAR-LC083 Anti-Mesothelin (M18) h(41BB-CD3ζ) CAR, pCDCAR1 Human M18 Human scFv-41BB-CD3ζ Lentiviral T cell   Inquiry
  Datasheet

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