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Mesothelin

Mesothelin also called MSLN is encoded by MSLN, which is a tumor differentiation antigen that is normally present on the mesothelial cells lining the pleura, peritoneum and pericardium. The limited mesothelin expression in normal tissues and high expression in many cancers makes it an attractive candidate for therapy. Mesothelin not only is related to mesothelioma, ovarian cancer, pancreatic cancer and lung cancer but also is associated with squamous cell carcinomas such as cervix, lung and head and neck carcinomas and adenocarcinomas.

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CAT Product Name Target Species Antibody Clone Antibody Host Receptor Construction Vector Type Targeting Cell Type Inquiry & Datasheet
CAR-T-1-M321-2 Anti-mesothelin scFv h(CD28) CART, pCDCAR1 Human SS1 Mouse scFv-CD28 Lentiviral T cell   Add to Cart   Datasheet
CAR-T-1-M321-G Anti-mesothelin scFv h(FcεRIγ) CART, pCDCAR1 Human SS1 Mouse scFv-FcεRIγ Lentiviral T cell   Add to Cart   Datasheet
CAR-T-1-M321-Z Anti-mesothelin scFv h(CD3ζ) CART, pCDCAR1 Human SS1 Mouse scFv-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-T-2-M321-2G Anti-mesothelin scFv h(CD28-FcεRIγ) CART, pCDCAR1 Human SS1 Mouse scFv-CD28-FcεRIγ Lentiviral T cell   Add to Cart   Datasheet
CAR-T-2-M321-2Z Anti-mesothelin scFv h(CD28-CD3ζ) CART, pCDCAR1 Human SS1 Mouse scFv-CD28-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-T-2-M321-4G Anti-mesothelin scFv h(CD4-FcεRIγ) CART, pCDCAR1 Human SS1 Mouse scFv-CD4-FcεRIγ Lentiviral T cell   Add to Cart   Datasheet
CAR-T-2-M321-8Z Anti-mesothelin scFv h(CD8-CD3ζ) CART, pCDCAR1 Human SS1 Mouse scFv-CD8-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-T-2-M321-BZ Anti-mesothelin scFv h(41BB-CD3ζ) CART, pCDCAR1 Human SS1 Mouse scFv-41BB-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-T-2-M321-CZ Anti-mesothelin scFv h(b2c-CD3ζ) CART, pCDCAR1 Human SS1 Mouse scFv-b2c-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-T-3-M321-2BZ Anti-mesothelin scFv h(CD28-41BB-CD3ζ) CART, pCDCAR1 Human SS1 Mouse scFv-CD28-41BB-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-T-3-M321-2XZ Anti-mesothelin scFv h(CD28-OX40-CD3ζ) CART, pCDCAR1 Human SS1 Mouse scFv-CD28-OX40-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-LC023 Anti-Mesothelin (m912) h(CD3ζ) CAR, pCDCAR1 Human m912 Human scFv-CD3ζ Retroviral T cell   Add to Cart   Datasheet
CAR-LC024 Anti-Mesothelin (m912) h(CD28-CD3ζ) CAR, pCDCAR1 Human m912 Human scFv-CD28-CD3ζ Retroviral T cell   Add to Cart   Datasheet
CAR-LC037 Anti-Mesothelin (SS1) h(ICOS-CD3ζ) CAR, pCDCAR1 Human SS1 Mouse scFv-ICOS-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-LC053 Anti-Mesothelin (HN1) h(CD28-CD3ζ) CAR, pCDCAR1 Human HN1 Human scFv-CD28-CD3ζ Retroviral T cell   Add to Cart   Datasheet
CAR-LC054 Anti-Mesothelin (HN1) h(CD28-41BB-CD3ζ) CAR, pCDCAR1 Human HN1 Human scFv-CD28-41BB-CD3ζ Retroviral T cell   Add to Cart   Datasheet
CAR-LC066 Anti-Mesothelin (M1) h(41BB-CD3ζ) CAR, pCDCAR1 Human M1 Human scFv-41BB-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-LC067 Anti-Mesothelin (M2) h(41BB-CD3ζ) CAR, pCDCAR1 Human M2 Human scFv-41BB-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-LC068 Anti-Mesothelin (M3) h(41BB-CD3ζ) CAR, pCDCAR1 Human M3 Human scFv-41BB-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-LC069 Anti-Mesothelin (M4) h(41BB-CD3ζ) CAR, pCDCAR1 Human M4 Human scFv-41BB-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-LC070 Anti-Mesothelin (M5) h(41BB-CD3ζ) CAR, pCDCAR1 Human M5 Human scFv-41BB-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-LC071 Anti-Mesothelin (M6) h(41BB-CD3ζ) CAR, pCDCAR1 Human M6 Human scFv-41BB-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-LC072 Anti-Mesothelin (M7) h(41BB-CD3ζ) CAR, pCDCAR1 Human M7 Human scFv-41BB-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-LC073 Anti-Mesothelin (M8) h(41BB-CD3ζ) CAR, pCDCAR1 Human M8 Human scFv-41BB-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-LC074 Anti-Mesothelin (M9) h(41BB-CD3ζ) CAR, pCDCAR1 Human M9 Human scFv-41BB-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-LC075 Anti-Mesothelin (M10) h(41BB-CD3ζ) CAR, pCDCAR1 Human M10 Human scFv-41BB-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-LC076 Anti-Mesothelin (M11) h(41BB-CD3ζ) CAR, pCDCAR1 Human M11 Human scFv-41BB-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-LC077 Anti-Mesothelin (M12) h(41BB-CD3ζ) CAR, pCDCAR1 Human M12 Human scFv-41BB-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-LC176 Anti-Mesothelin (P4) h(CD3ζ) CAR, pCDCAR1 Human P4 Human scFv-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-LC177 Anti-Mesothelin (P4) h(CD28-CD3ζ) CAR, pCDCAR1 Human P4 Human scFv-CD28-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-LC268 Anti-MSLN (HN1) h(41BB/CD3ζ, FKBP/FRB) Conditional CAR, pCDCAR1 Human HN1 Human scFv-41BB-FKBP/41BB-FRB-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-LC269 Anti-MSLN (SS1) h(41BB/CD3ζ, FKBP/FRB) Conditional CAR, pCDCAR1 Human SS1 Mouse scFv-41BB-FKBP/41BB-FRB-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-LC270 Anti-MSLN (m912) h(41BB/CD3ζ, FKBP/FRB) Conditional CAR, pCDCAR1 Human m912 Human scFv-41BB-FKBP/41BB-FRB-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-LC370 Anti-MSLN (SS1) h(KIR2DS2, DAP12) Armoured CAR, pCDCAR1 Human SS1 Mouse scFv-KIR2DS2 Lentiviral T cell   Add to Cart   Datasheet
CAR-YF116 Anti-Mesothelin (m912) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human m912 Human scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-YF157 Anti-Mesothelin (CBL-YF049) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human CBL-YF049 Humanized scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-YF158 Anti-Mesothelin (CBL-YF049) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBL-YF049 Humanized scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP074 Anti-Mesothelin (M13) h(CD28-CD3ζ) CAR, pCDCAR1 Human M13 Human scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP8814 Anti-Mesothelin (BA0185) h(CD28-CD3ζ) CAR, pcDCAR1 EBV BA0185 Rabbit scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP8815 Anti-Mesothelin (BA0185) h(4-1BB-CD3ζ) CAR, pcDCAR1 EBV BA0185 Rabbit scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet

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