Creative Biolabs is offering the most comprehensive services for antibody development projects. With strict regulation and effective execution, we are dedicated to providing the most valuable solutions to complete your projects.
HighlightsCreative Biolabs is offering the most comprehensive services for antibody development projects. With strict regulation and effective execution, we are dedicated to providing the most valuable solutions to complete your projects.
HighlightsCreative Biolabs has established a broad range of platforms for developing novel antibodies or equivalents. These cutting-edge technologies enable our scientists to meet your demands from different aspects and tailor the most appropriate solution that contributes to the success of your projects.
HighlightsWith deep understanding in antibody-related realms and extensive project experience, Creative Biolabs offers a variety of references to help you learn more about our capacities and achievements, including infographic, flyer, case study, peer-reviewed publications, and all kinds of knowledge that can assist your projects. You are also welcome to contact us directly for more specific solutions.
HighlightsGet a real taste of Creative Biolabs, one of the most professional custom service providers in the world. We are committed to providing highly customized comprehensive solutions with the best quality to advance your projects.
HighlightsMonocytes and macrophages play crucial roles in the innate immune system, contributing to various physiological functions such as tissue maintenance, pathogen defense, and immune response regulation. Upon encountering inflammatory stimuli, these versatile cells display remarkable plasticity, adapting and transforming into distinct subsets based on the surrounding microenvironment. Creative Biolabs provides a macrophage/monocyte inflammation stimulation assay service to advance therapeutics development.
Fig. 1 Macrophages/monocytes: key players of the innate immune system.1
Our macrophage/monocyte inflammation stimulation assay service leverages advanced expertise and technologies to evaluate the effect of candidate compounds on macrophage/monocyte inflammation in a gradient-dependent manner. We provide various ready-to-use PBMCs and also are able to isolate PBMCs from fresh blood. Of course, if customers have unique requirements, we have the capacity to customize your experiment scheme.
For the inflammation examination, we offer cutting-edge technologies based on our well-equipped platform to analyze cytokine release, cell chemotaxis, etc. Throughout the process, Creative Biolabs provides a full range of services encompassing cell preparation, inflammation induction, compound incubation, inflammation analysis, and results visualization.
Fig. 2 Workflow of our macrophage/monocyte inflammation stimulation assay.
| M1 monocyte/macrophage (CD68+ cells) panel: | M2 monocyte/macrophage (CD68+ cells) panel: | CXCL monocyte/macrophage (CD68+ cells) panel: |
|
Anti-human TNFα antibody Anti-human IL-6 antibody Anti-human MCP-1 antibody |
Anti-human IL-10 antibody Anti-human arginase-1 antibody Anti-human PD-L1 antibody |
Anti-human CXCL9 antibody Anti-human CXC10 antibody Anti-human CXCL11 antibody |
In addition to antibody staining, the fluorescent dye is an alternative option for macrophage/monocyte inflammation stimulation evaluation. Creative Biolabs brings out a number of fluorescent dyes to design for customers' projects with diverse demands:
Q1: How to stimulate monocytes and macrophages in this service?
A1: Our service takes advantage of LPS, bacteria, pro-inflammatory cytokines, and other factors to trigger the inflammation reaction of macrophages/monocytes. At the same time, we treat macrophages/monocytes with customers' candidate samples. By monitoring the inflammation variation, we evaluate the effectiveness and efficacy of your candidate samples in the laboratory setting.
Q2: What are the requirements for samples in macrophage/monocyte inflammation stimulation assay service?
A2: We need customers to provide some basic information, such as testing samples, molecular weight, concentration, etc. For PBMC, customers are capable of executing your projects with PBMCs provided by Creative Biolabs, or you supply us with selected PBMCs. Noteworthy, when you transport your selected PBMCs, it is possible to cause cell death or viability decreased. Furthermore, if your projects are characterized by special requirements, please contact our team of experts directly to help you.
For more details about our macrophage/monocyte inflammation stimulation assay service, please feel free to get in touch with us.
Reference
All listed services and products are For Research Use Only. Do Not use in any diagnostic or therapeutic applications.
