Magic™ Membrane Protein Human CCR6 (C-C motif chemokine receptor 6) for Antibody Discovery (CAT#: MP0172X)

Datasheet

This product is a 42.5 kDa Human CCR6 membrane protein expressed in in vitro wheat germ expression system with proprietary liposome technology. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

Host Species
Human

Target Protein
CCR6

Protein Length
Full-length

Molecular Weight
42.5 kDa

Sequence
MSGESMNFSDVFDSSEDYFVSVNTSYYSVDSEMLLCSLQEVRQFSRLFVPIAYSLICVFGLLGNILVVITFAFYKKARSMTDVYLLNMAIADILFVLTLPFWAVSHATGAWVFSNATCKLLKGIYAINFNCGMLLLTCISMDRYIAIVQATKSFRLRSRTLPRSKIICLVVWGLSVIISSSTFVFNQKYNTQGSDVCEPKYQTVSEPIRWKLLMLGLELLFGFFIPLMFMIFCYTFIVKTLVQAQNSKRHKAIRVIIAVVLVFLACQIPHNMVLLVTAANLGKMNRSCQSEKLIGYTKTVTEVLAFLHCCLNPVLYAFIGQKFRNYFLKILKDLWCVRRKYKSSGFSCAGRYSENISRQTSETADNDNASSFTM

Product Description

Application
Antibody Production

Expression Systems
in vitro wheat germ expression system with proprietary liposome technology

Purification
None

Buffer
25 mM Tris-HCl of pH8.0 containing 2% glycerol

Target

Target Protein
CCR6

Full Name
C-C motif chemokine receptor 6

Introduction
This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The gene is preferentially expressed by immature dendritic cells and memory T cells. The ligand of this receptor is macrophage inflammatory protein 3 alpha (MIP-3 alpha). This receptor has been shown to be important for B-lineage maturation and antigen-driven B-cell differentiation, and it may regulate the migration and recruitment of dentritic and T cells during inflammatory and immunological responses. Alternatively spliced transcript variants that encode the same protein have been described for this gene

Alternative Names
BN-1; CD196; CKR-L3; CKR6; CKRL3; CMKBR6; DCR2; DRY-6; GPR-CY4; GPR29; GPRCY4; STRL22; G protein-coupled receptor 29; OTTHUMP00000017618; OTTHUMP00000017619; chemokine (C-C) receptor 6; chemokine receptor-like 3; seven-transmembrane receptor; lymphocyte, 22; G protein-coupled receptor 29; OTTHUMP00000017618; OTTHUMP00000017619; chemokine (C-C) receptor 6; chemokine receptor-like 3; seven-transmembrane receptor, lymphocyte, 22

Gene ID
1235

UniProt ID
P51684

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