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MemDX™ Mouse TLR8 HEK293 Cell Line with SEAP Reporter (CAT#: S01YF-0123-KX408)

This product is a HEK293 stable cell line. It stably expresses Mouse TLR8 to provide cell models for research and screening applications.

Product Information

  • Target Protein
  • TLR8
  • Target Protein Species
  • Mouse
  • Host Cell Type
  • HEK293
  • Target Classification
  • Immune Checkpoint
  • Target Family
  • Immune Checkpoint
  • Target Research Area
  • Autoimmune Research; Immunology Research
  • Related Diseases
  • Immunodeficiency; Anemia, Autoimmune Hemolytic

Product Properties

  • Morphology
  • Adherent
  • Assay Types
  • Drug screening and biological assays
  • Assay Reporter
  • SEAP
  • Mycoplasma Testing
  • Negative
  • Biosafety Level
  • Level 1
  • Activity
  • Yes
  • Quantity
  • 3x10⁶ cells
  • Form
  • Frozen cells
  • Selective Antibiotic(s)
  • Regular antibiotics active against mycoplasmas, bacteria and fungi.
  • Handling Notes
  • Frozen cells should be thawed immediately upon receipt and grown according to handling procedure to ensure cell viability and proper assay performance.
    Note: Do not freeze the cells upon receipt as it may result in irreversible damage to the cell line.
    Disclaimer: We cannot guarantee cell viability if the cells are not thawed immediately upon receipt and grown according to handling procedure.
  • Incubation
  • 37°C with 5% CO₂
  • Applications
  • Drug screening and biological assays
  • Application Notes
  • Cells were plated in a 384-well plate and incubated overnight at 37°C and 5% CO₂ to allow the cells to attach and grow. Cells were then stimulated with a control for high-throughput drugs screening andfunctional assays.
  • Use Restrictions
  • These cells are distributed for research use only.
  • Shipping
  • Dry ice
  • Storage
  • Liquid nitrogen

Target

  • Full Name
  • Toll-like receptor 8
  • Introduction
  • Predicted to enable identical protein binding activity; nucleic acid binding activity; and pattern recognition receptor activity. Acts upstream of or within regulation of protein phosphorylation. Predicted to be located in external side of plasma membrane. Predicted to be active in plasma membrane. Is expressed in brain and liver. Orthologous to human TLR8 (toll like receptor 8).
  • Alternative Names
  • TLR8; toll-like receptor 8

Case Studies

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