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NativeExtract™ Human F2RL1 Membrane Protein (Full length, Super Nanodisc) (CAT#: S01YF-1023-KX469)

Datasheet
This product is recombinant Human F2RL1 protein in native nanodisc form. The synthetic compound we developed can solubilize the F2RL1 protein from membrane while retaining the native structure.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • F2RL1
  • Protein Length
  • Full length
  • Molecular Weight
  • 44.1 kDa

Product Description

  • Activity
  • Yes
  • Application
  • ELISA; SPR Binding Assays; Phage Display Screening; Immunity; Functional Assays
  • Expression Systems
  • HEK293 expression system
  • Tag
  • Flag tag at the C-terminus
  • Protein Format
  • Native Nanodisc
  • Buffer
  • 20 mM Tris-HCl, 150 mM NaCl, pH 8.0

Target

  • Target Protein
  • F2RL1
  • Full Name
  • F2R like trypsin receptor 1
  • Introduction
  • This gene encodes a member of the G-protein coupled receptor 1 family of proteins. The encoded cell surface receptor is activated through proteolytic cleavage of its extracellular amino terminus, resulting in a new amino terminus that acts as a tethered ligand that binds to an extracellular loop domain. Activation of the receptor has been shown to stimulate vascular smooth muscle relaxation, dilate blood vessels, increase blood flow, and lower blood pressure. This protein is also important in the inflammatory response, as well as innate and adaptive immunity.
  • Alternative Names
  • PAR2; GPR11; proteinase-activated receptor 2; G-protein coupled receptor 11; coagulation factor II (thrombin) receptor-like 1; protease-activated receptor 2; thrombin receptor-like 1; F2RL1; F2R like trypsin receptor 1

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