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MemDX™ Antibody Discovery - Cynomolgus / Rhesus macaque FOLR1 (25-233) Membrane Protein, Partial, -His tag (CAT#: MP0086F)

Datasheet
This membrane protein is Cynomolgus / Rhesus macaque FOLR1 (25-233). It has been tested in SDS-PAGE, ELISA. We provide this protein to facilitate your membrane protein antibody discovery and development.

Product Specifications

  • Host Species
  • Cynomolgus / Rhesus macaque
  • Target Protein
  • FOLR1
  • Protein Length
  • ECD
  • Molecular Weight
  • The protein has a calculated MW of 26.4 kDa. The protein migrates as 35-41 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
  • Sequence
  • AA Arg 25 - Met 233 (Accession # NP_001181576.1).

Product Description

  • Activity
  • Yes
  • Application
  • SDS-PAGE, ELISA
  • Expression Systems
  • HEK293
  • Tag
  • His tag at the C-terminus
  • Protein Format
  • Soluble
  • Reconstitution
  • Please see Certificate of Analysis for specific instructions.
  • Endotoxin
  • <1.0 EU/μg by the LAL method
  • Purity
  • >90% as determined by SDS-PAGE.
  • Buffer
  • Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization.

Target

  • Target Protein
  • FOLR1
  • Full Name
  • folate receptor alpha
  • Introduction
  • The protein encoded by this gene is a member of the folate receptor family. Members of this gene family bind folic acid and its reduced derivatives, and transport 5-methyltetrahydrofolate into cells. This gene product is a secreted protein that either anchors to membranes via a glycosyl-phosphatidylinositol linkage or exists in a soluble form. Mutations in this gene have been associated with neurodegeneration due to cerebral folate transport deficiency. Due to the presence of two promoters, multiple transcription start sites, and alternative splicing, multiple transcript variants encoding the same protein have been found for this gene
  • Alternative Names
  • FBP; FOLR; NCFTD; Fralpha; folate receptor alpha; FR-alpha; KB cells FBP; adult folate-binding protein; folate binding protein; folate receptor 1 (adult); folate receptor, adult; ovarian tumor-associated antigen MOv18

Case Studies

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