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Magic™ Recombinant Human TRPM4 Membrane Protein in Virus-Like Particles (MP-VLPs) (CAT#: MPVLP-024)

This product is recombinant Human TRPM4 in VLPs form. This product is produced from mammalian cells by co-expressing the retroviral structural core polyprotein (gag) and the target membrane protein. MP-VLPs display highly-expressed copies of membrane proteins in their native conformation, providing an alternative to membrane protein stable cell lines, membrane preparations, detergent-solubilized proteins and other membrane protein preparation strategies. MP-VLPs can be used for a wide range of applications in antibody production, antibody discovery, antibody characterization, binding assays and functional assays.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • TRPM4
  • Protein Length
  • Full length
  • Protein Class
  • Ion channel
  • TMD
  • 6

Product Description

  • Application
  • ELISA; Antibody Production; Antibody Discovery; Antibody Characterization; Binding Assays; Functional Assays
  • Expression Systems
  • HEK293 expression system
  • Protein Format
  • Membrane Protein-Virus Like Particles (MP-VLPs)

Target

  • Target Protein
  • TRPM4
  • Full Name
  • Transient receptor potential cation channel subfamily M member 4
  • Introduction
  • The protein encoded by this gene is a calcium-activated nonselective ion channel that mediates transport of monovalent cations across membranes, thereby depolarizing the membrane. The activity of the encoded protein increases with increasing intracellular calcium concentration, but this channel does not transport calcium.
  • Alternative Names
  • EKVP6; LTrpC4; PFHB1B; TRPM4B; hTRPM4; transient receptor potential cation channel subfamily M member 4; calcium-activated non-selective cation channel 1; long transient receptor potential channel 4; melastatin-4

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