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MemDX™ Membrane Protein Human PPT1 (Palmitoyl-protein thioesterase 1) Expressed in vitro Wheat Germ expression system, Full Length (CAT#: MPX1982K)

This product is a Human PPT1 protein expressed in vitro Wheat Germ expression system. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • PPT1
  • Protein Length
  • Full Length
  • Protein Class
  • Hydrolase
  • Molecular Weight
  • 60.6 kDa
  • Sequence
  • MASPGCLWLLAVALLPWTCASRALQHLDPPAPLPLVIWHGMGDSCCNPLSMGAIKKMVEKKIPGIYVLSLEIGKTLMEDVENSFFLNVNSQVTTVCQALAKDPKLQQGYNAMGFSQGGQFLRAVAQRCPSPPMINLISVGGQHQGVFGLPRCPGESSHICDFIRKTLNAGAYSKVVQERLVQAEYWHDPIKEDVYRNHSIFLADINQERGINESYKKNLMALKKFVMVKFLNDSIVDPVDSEWFGFYRSGQAKETIPLQETSLYTQDRLGLKEMDNAGQLVFLATEGDHLQLSEEWFYAHIIPFLG

Product Description

  • Expression Systems
  • in vitro Wheat Germ expression system
  • Tag
  • GST tag at the N-terminus
  • Protein Format
  • Soluble
  • Buffer
  • 50 mM Tris-HCI, 10 mM reduced Glutathione, pH8.0

Target

  • Target Protein
  • PPT1
  • Full Name
  • Palmitoyl-protein thioesterase 1
  • Introduction
  • The protein encoded by this gene is a small glycoprotein involved in the catabolism of lipid-modified proteins during lysosomal degradation. The encoded enzyme removes thioester-linked fatty acyl groups such as palmitate from cysteine residues. Defects in this gene are a cause of infantile neuronal ceroid lipofuscinosis 1 (CLN1, or INCL) and neuronal ceroid lipofuscinosis 4 (CLN4). Two transcript variants encoding different isoforms have been found for this gene.
  • Alternative Names
  • PPT; CLN1; INCL; palmitoyl-protein thioesterase 1; ceroid-palmitoyl-palmitoyl-protein thioesterase 1; palmitoyl-protein hydrolase 1

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