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NativeExtract™ Human ADGRL3 Membrane Protein (Full length, Super Nanodisc) (CAT#: S01YF-1023-KX304)

This product is recombinant Human ADGRL3 protein in native nanodisc form. The synthetic compound we developed can solubilize the ADGRL3 protein from membrane while retaining the native structure.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • ADGRL3
  • Protein Length
  • Full length
  • Molecular Weight
  • 161.8kDa

Product Description

  • Activity
  • Yes
  • Application
  • ELISA; SPR Binding Assays; Phage Display Screening; Immunity; Functional Assays
  • Expression Systems
  • HEK293 expression system
  • Tag
  • Flag tag at the C-terminus
  • Protein Format
  • Native Nanodisc
  • Buffer
  • 20 mM Tris-HCl, 150 mM NaCl, pH 8.0

Target

  • Target Protein
  • ADGRL3
  • Full Name
  • Adhesion G protein-coupled receptor L3
  • Introduction
  • This gene encodes a member of the latrophilin subfamily of G-protein coupled receptors (GPCR). Latrophilins may function in both cell adhesion and signal transduction. In experiments with non-human species, endogenous proteolytic cleavage within a cysteine-rich GPS (G-protein-coupled-receptor proteolysis site) domain resulted in two subunits (a large extracellular N-terminal cell adhesion subunit and a subunit with substantial similarity to the secretin/calcitonin family of GPCRs) being non-covalently bound at the cell membrane.
  • Alternative Names
  • CL3; LEC3; CIRL3; LPHN3; calcium-independent alpha-latrotoxin receptor 3; latrophilin homolog 3 (cow); latrophilin-3; lectomedin 3; ADGRL3; Adhesion G protein-coupled receptor L3

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