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NativeExtract™ Human AVPR1B Membrane Protein (Full length, Super Nanodisc) (CAT#: S01YF-1023-KX22)

This product is recombinant Human AVPR1B protein in native nanodisc form. The synthetic compound we developed can solubilize the AVPR1B protein from membrane while retaining the native structure.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • AVPR1B
  • Protein Length
  • Full length
  • Molecular Weight
  • 47kDa

Product Description

  • Activity
  • Yes
  • Application
  • ELISA; SPR Binding Assays; Phage Display Screening; Immunity; Functional Assays
  • Expression Systems
  • HEK293 expression system
  • Tag
  • Flag tag at the C-terminus
  • Protein Format
  • Native Nanodisc
  • Buffer
  • 20 mM Tris-HCl, 150 mM NaCl, pH 8.0

Target

  • Target Protein
  • AVPR1B
  • Full Name
  • Arginine vasopressin receptor 1B
  • Introduction
  • The protein encoded by this gene acts as receptor for arginine vasopressin. This receptor belongs to the subfamily of G-protein coupled receptors which includes AVPR1A, V2R and OXT receptors. Its activity is mediated by G proteins which stimulate a phosphatidylinositol-calcium second messenger system. The receptor is primarily located in the anterior pituitary, where it stimulates ACTH release. It is expressed at high levels in ACTH-secreting pituitary adenomas as well as in bronchial carcinoids responsible for the ectopic ACTH syndrome. A spliced antisense transcript of this gene has been reported but its function is not known.
  • Alternative Names
  • V1bR; AVPR3; AVPR V1b; AVPR V3; antidiuretic hormone receptor 1B; arginine vasopressin receptor 3; pituitary vasopressin receptor 3; vasopressin V3 receptor; AVPR1B; Arginine vasopressin receptor 1B

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