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NativeExtract™ Human CCR4 Membrane Protein (Full length, Super Nanodisc) (CAT#: S01YF-1023-KX479)

Datasheet
This product is recombinant Human CCR4 protein in native nanodisc form. The synthetic compound we developed can solubilize the CCR4 protein from membrane while retaining the native structure.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • CCR4
  • Protein Length
  • Full length
  • Molecular Weight
  • 41.4 kDa

Product Description

  • Activity
  • Yes
  • Application
  • ELISA; SPR Binding Assays; Phage Display Screening; Immunity; Functional Assays
  • Expression Systems
  • HEK293 expression system
  • Tag
  • Flag tag at the C-terminus
  • Protein Format
  • Native Nanodisc
  • Buffer
  • 20 mM Tris-HCl, 150 mM NaCl, pH 8.0

Target

  • Target Protein
  • CCR4
  • Full Name
  • C-C motif chemokine receptor 4
  • Introduction
  • The protein encoded by this gene belongs to the G-protein-coupled receptor family . It is a receptor for the CC chemokine - MIP-1, RANTES, TARC and MCP-1. Chemokines are a group of small polypeptide, structurally related molecules that regulate cell trafficking of various types of leukocytes. The chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis.
  • Alternative Names
  • CKR4; K5-5; CD194; CMKBR4; ChemR13; CC-CKR-4; HGCN:14099;C-C chemokine receptor type 4;C-C CKR-4;CCR-4;chemokine (C-C motif) receptor 4;chemokine (C-C) receptor 4;CCR4

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