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NativeExtract™ Human CCRL2 Membrane Protein (Full length, Super Nanodisc) (CAT#: S01YF-1023-KX293)

Datasheet
This product is recombinant Human CCRL2 protein in native nanodisc form. The synthetic compound we developed can solubilize the CCRL2 protein from membrane while retaining the native structure.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • CCRL2
  • Protein Length
  • Full length
  • Molecular Weight
  • 39.5kDa

Product Description

  • Activity
  • Yes
  • Application
  • ELISA; SPR Binding Assays; Phage Display Screening; Immunity; Functional Assays
  • Expression Systems
  • HEK293 expression system
  • Tag
  • Flag tag at the C-terminus
  • Protein Format
  • Native Nanodisc
  • Buffer
  • 20 mM Tris-HCl, 150 mM NaCl, pH 8.0

Target

  • Target Protein
  • CCRL2
  • Full Name
  • C-C motif chemokine receptor like 2
  • Introduction
  • This gene encodes a chemokine receptor like protein, which is predicted to be a seven transmembrane protein and most closely related to CCR1. Chemokines and their receptors mediated signal transduction are critical for the recruitment of effector immune cells to the site of inflammation. This gene is expressed at high levels in primary neutrophils and primary monocytes, and is further upregulated on neutrophil activation and during monocyte to macrophage differentiation. The function of this gene is unknown. This gene is mapped to the region where the chemokine receptor gene cluster is located.
  • Alternative Names
  • HCR; CKRX; CRAM; ACKR5; CRAM-A; CRAM-B; C-C chemokine receptor-like 2; atypical chemokine receptor 5; chemokine (C-C motif) receptor-like 2; chemokine receptor CCR11; chemokine receptor X; putative MCP-1 chemokine receptor; CCRL2; C-C motif chemokine receptor like 2

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