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NativeExtract™ Human CELSR3 Membrane Protein (Full length, Super Nanodisc) (CAT#: S01YF-1023-KX290)

This product is recombinant Human CELSR3 protein in native nanodisc form. The synthetic compound we developed can solubilize the CELSR3 protein from membrane while retaining the native structure.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • CELSR3
  • Protein Length
  • Full length
  • Molecular Weight
  • 358.2kDa

Product Description

  • Activity
  • Yes
  • Application
  • ELISA; SPR Binding Assays; Phage Display Screening; Immunity; Functional Assays
  • Expression Systems
  • HEK293 expression system
  • Tag
  • Flag tag at the C-terminus
  • Protein Format
  • Native Nanodisc
  • Buffer
  • 20 mM Tris-HCl, 150 mM NaCl, pH 8.0

Target

  • Target Protein
  • CELSR3
  • Full Name
  • Cadherin EGF LAG seven-pass G-type receptor 3
  • Introduction
  • This gene belongs to the flamingo subfamily, which is included in the cadherin superfamily. The flamingo cadherins consist of nonclassic-type cadherins that do not interact with catenins. They are plasma membrane proteins containing seven epidermal growth factor-like repeats, nine cadherin domains and two laminin A G-type repeats in their ectodomain. They also have seven transmembrane domains, a characteristic feature of their subfamily. The encoded protein may be involved in the regulation of contact-dependent neurite growth and may play a role in tumor formation.
  • Alternative Names
  • FMI1; EGFL1; HFMI1; MEGF2; ADGRC3; CDHF11; RESDA1; cadherin EGF LAG seven-pass G-type receptor 3; EGF-like protein 1; EGF-like-domain, multiple 1; adhesion G protein-coupled; receptor C3; anchor protein; cadherin family member 11; cadherin, EGF LAG seven-pass G-type receptor 3 (flamingo homolog, Drosophila); epidermal growth factor-like protein 1; flamingo homolog 1; multiple EGF-like domains protein 2; multiple epidermal growth factor-like domains protein 2; CELSR3; Cadherin EGF LAG seven-pass G-type receptor 3

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