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NativeExtract™ Human CLDN2 Membrane Protein (Full length, Super Nanodisc) (CAT#: S01YF-1023-KX411)

This product is recombinant Human CLDN2 protein in native nanodisc form. The synthetic compound we developed can solubilize the CLDN2 protein from membrane while retaining the native structure.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • CLDN2
  • Protein Length
  • Full length
  • Molecular Weight
  • 24.5 kDa

Product Description

  • Activity
  • Yes
  • Application
  • ELISA; SPR Binding Assays; Phage Display Screening; Immunity; Functional Assays
  • Expression Systems
  • HEK293 expression system
  • Tag
  • Flag tag at the C-terminus
  • Protein Format
  • Native Nanodisc
  • Buffer
  • 20 mM Tris-HCl, 150 mM NaCl, pH 8.0

Target

  • Target Protein
  • CLDN2
  • Full Name
  • Claudin 2
  • Introduction
  • This gene product belongs to the claudin protein family whose members have been identified as major integral membrane proteins localized exclusively at tight junctions. Claudins are expressed in an organ-specific manner and regulate tissue-specific physiologic properties of tight junctions. This protein is expressed in the intestine. Alternatively spliced transcript variants with different 5' untranslated region have been found for this gene.
  • Alternative Names
  • CLDN2; OAZON; claudin-2; SP82; Claudin 2

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