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NativeExtract™ Human CLDN9 Membrane Protein (Full length, Super Nanodisc) (CAT#: S01YF-1023-KX412)

This product is recombinant Human CLDN9 protein in native nanodisc form. The synthetic compound we developed can solubilize the CLDN9 protein from membrane while retaining the native structure.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • CLDN9
  • Protein Length
  • Full length
  • Molecular Weight
  • 22.8 kDa

Product Description

  • Activity
  • Yes
  • Application
  • ELISA; SPR Binding Assays; Phage Display Screening; Immunity; Functional Assays
  • Expression Systems
  • HEK293 expression system
  • Tag
  • Flag tag at the C-terminus
  • Protein Format
  • Native Nanodisc
  • Buffer
  • 20 mM Tris-HCl, 150 mM NaCl, pH 8.0

Target

  • Target Protein
  • CLDN9
  • Full Name
  • Claudin 9
  • Introduction
  • This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This protein is one of the entry cofactors for hepatitis C virus. Mouse studies revealed that this gene is required for the preservation of sensory cells in the hearing organ and the gene deficiency is associated with deafness.
  • Alternative Names
  • CLDN9; DFNB116; claudin-9; Claudin 9

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