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NativeExtract™ Human CNR1 Membrane Protein (Full length, Super Nanodisc) (CAT#: S01YF-1023-KX480)

Datasheet
This product is recombinant Human CNR1 protein in native nanodisc form. The synthetic compound we developed can solubilize the CNR1 protein from membrane while retaining the native structure.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • CNR1
  • Protein Length
  • Full length
  • Molecular Weight
  • 52.7 kDa

Product Description

  • Activity
  • Yes
  • Application
  • ELISA; SPR Binding Assays; Phage Display Screening; Immunity; Functional Assays
  • Expression Systems
  • HEK293 expression system
  • Tag
  • Flag tag at the C-terminus
  • Protein Format
  • Native Nanodisc
  • Buffer
  • 20 mM Tris-HCl, 150 mM NaCl, pH 8.0

Target

  • Target Protein
  • CNR1
  • Full Name
  • Cannabinoid receptor 1
  • Introduction
  • This gene encodes one of two cannabinoid receptors. The cannabinoids, principally delta-9-tetrahydrocannabinol and synthetic analogs, are psychoactive ingredients of marijuana. The cannabinoid receptors are members of the guanine-nucleotide-binding protein (G-protein) coupled receptor family, which inhibit adenylate cyclase activity in a dose-dependent, stereoselective and pertussis toxin-sensitive manner. The two receptors have been found to be involved in the cannabinoid-induced CNS effects (including alterations in mood and cognition) experienced by users of marijuana. Multiple transcript variants encoding two different protein isoforms have been described for this gene.
  • Alternative Names
  • CB1; CNR; CB-R; CB1A; CB1R; CANN6; CB1K5; cannabinoid receptor 1 (brain); central cannabinoid receptor; CNR1; Cannabinoid receptor 1

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