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NativeExtract™ Human GPR151 Membrane Protein (Full length, Super Nanodisc) (CAT#: S01YF-1023-KX242)

Datasheet
This product is recombinant Human GPR151 protein in native nanodisc form. The synthetic compound we developed can solubilize the GPR151 protein from membrane while retaining the native structure.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • GPR151
  • Protein Length
  • Full length
  • Molecular Weight
  • 46.6kDa

Product Description

  • Activity
  • Yes
  • Application
  • ELISA; SPR Binding Assays; Phage Display Screening; Immunity; Functional Assays
  • Expression Systems
  • HEK293 expression system
  • Tag
  • Flag tag at the C-terminus
  • Protein Format
  • Native Nanodisc
  • Buffer
  • 20 mM Tris-HCl, 150 mM NaCl, pH 8.0

Target

  • Target Protein
  • GPR151
  • Full Name
  • G protein-coupled receptor 151
  • Introduction
  • This gene encodes an orphan member of the class A rhodopsin-like family of G-protein-coupled receptors (GPCRs). Within the rhodopsin-like family, this gene is a member of the SOG subfamily that includes somatostatin, opioid, galanin, and kisspeptin receptors. The orthologous mouse gene has a restricted pattern of neuronal expression which is induced following nerve injury. All GPCRs have a transmembrane domain that includes seven transmembrane alpha-helices. A general feature of GPCR signaling is the agonist-induced conformational change in the receptor, leading to activation of the heterotrimeric G protein. The activated G protein then binds to and activates numerous downstream effector proteins, which generate second messengers that mediate a broad range of cellular and physiological processes.
  • Alternative Names
  • GPCR; PGR7; GALR4; GALRL; GPCR-2037; G-protein coupled receptor 151; G-protein coupled receptor PGR7; galanin receptor 4; galanin-receptor-like protein; GPR151; G protein-coupled receptor 151

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