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NativeExtract™ Human GPR78 Membrane Protein (Full length, Super Nanodisc) (CAT#: S01YF-1023-KX196)

Datasheet
This product is recombinant Human GPR78 protein in native nanodisc form. The synthetic compound we developed can solubilize the GPR78 protein from membrane while retaining the native structure.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • GPR78
  • Protein Length
  • Full length
  • Molecular Weight
  • 39.3kDa

Product Description

  • Activity
  • Yes
  • Application
  • ELISA; SPR Binding Assays; Phage Display Screening; Immunity; Functional Assays
  • Expression Systems
  • HEK293 expression system
  • Tag
  • Flag tag at the C-terminus
  • Protein Format
  • Native Nanodisc
  • Buffer
  • 20 mM Tris-HCl, 150 mM NaCl, pH 8.0

Target

  • Target Protein
  • GPR78
  • Full Name
  • G protein-coupled receptor 78
  • Introduction
  • The protein encoded by this gene belongs to the G protein-coupled receptor family, which contain 7 transmembrane domains and transduce extracellular signals through heterotrimeric G proteins. This is an orphan receptor, which displays significant level of constitutive activity. Association analysis shows preliminary evidence for the involvement of this gene in susceptibility to bipolar affective disorder and schizophrenia. Alternatively spliced transcript variants have been found for this gene.
  • Alternative Names
  • G-protein coupled receptor 78; UNQ5925; PRO19818; GPR78; G protein-coupled receptor 78

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