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NativeExtract™ Human HRH2 Membrane Protein (Full length, Super Nanodisc) (CAT#: S01YF-1023-KX182)

Datasheet
This product is recombinant Human HRH2 protein in native nanodisc form. The synthetic compound we developed can solubilize the HRH2 protein from membrane while retaining the native structure.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • HRH2
  • Protein Length
  • Full length
  • Molecular Weight
  • 40.1kDa

Product Description

  • Activity
  • Yes
  • Application
  • ELISA; SPR Binding Assays; Phage Display Screening; Immunity; Functional Assays
  • Expression Systems
  • HEK293 expression system
  • Tag
  • Flag tag at the C-terminus
  • Protein Format
  • Native Nanodisc
  • Buffer
  • 20 mM Tris-HCl, 150 mM NaCl, pH 8.0

Target

  • Target Protein
  • HRH2
  • Full Name
  • Histamine receptor H2
  • Introduction
  • Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by histamine receptors H1, H2, H3 and H4. Histamine receptor H2 belongs to the family 1 of G protein-coupled receptors. It is an integral membrane protein and stimulates gastric acid secretion. It also regulates gastrointestinal motility and intestinal secretion and is thought to be involved in regulating cell growth and differentiation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
  • Alternative Names
  • H2R; HH2R; gastric receptor 1; gastric receptor I; HRH2; Histamine receptor H2

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