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NativeExtract™ Human MTNR1A Membrane Protein (Full length, Super Nanodisc) (CAT#: S01YF-1023-KX157)

Datasheet
This product is recombinant Human MTNR1A protein in native nanodisc form. The synthetic compound we developed can solubilize the MTNR1A protein from membrane while retaining the native structure.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • MTNR1A
  • Protein Length
  • Full length
  • Molecular Weight
  • 39.4kDa

Product Description

  • Activity
  • Yes
  • Application
  • ELISA; SPR Binding Assays; Phage Display Screening; Immunity; Functional Assays
  • Expression Systems
  • HEK293 expression system
  • Tag
  • Flag tag at the C-terminus
  • Protein Format
  • Native Nanodisc
  • Buffer
  • 20 mM Tris-HCl, 150 mM NaCl, pH 8.0

Target

  • Target Protein
  • MTNR1A
  • Full Name
  • Melatonin receptor 1A
  • Introduction
  • This gene encodes one of two high affinity forms of a receptor for melatonin, the primary hormone secreted by the pineal gland. This receptor is a G-protein coupled, 7-transmembrane receptor that is responsible for melatonin effects on mammalian circadian rhythm and reproductive alterations affected by day length. The receptor is an integral membrane protein that is readily detectable and localized to two specific regions of the brain. The hypothalamic suprachiasmatic nucleus appears to be involved in circadian rhythm while the hypophysial pars tuberalis may be responsible for the reproductive effects of melatonin.
  • Alternative Names
  • MT1; MEL-1A-R; melatonin receptor type 1A; mel1a receptor; MTNR1A; Melatonin receptor 1A

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