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NativeExtract™ Human NMBR Membrane Protein (Full length, Super Nanodisc) (CAT#: S01YF-1023-KX151)

Datasheet
This product is recombinant Human NMBR protein in native nanodisc form. The synthetic compound we developed can solubilize the NMBR protein from membrane while retaining the native structure.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • NMBR
  • Protein Length
  • Full length
  • Molecular Weight
  • 43.4kDa

Product Description

  • Activity
  • Yes
  • Application
  • ELISA; SPR Binding Assays; Phage Display Screening; Immunity; Functional Assays
  • Expression Systems
  • HEK293 expression system
  • Tag
  • Flag tag at the C-terminus
  • Protein Format
  • Native Nanodisc
  • Buffer
  • 20 mM Tris-HCl, 150 mM NaCl, pH 8.0

Target

  • Target Protein
  • NMBR
  • Full Name
  • Neuromedin B receptor
  • Introduction
  • This gene encodes a 7-transmembrane G protein-coupled receptor that binds neuromedin B, which is a growth factor and mitogen for gastrointestinal epithelial tissue and for normal and neoplastic lung. This receptor may play a role in smooth muscle contraction, neuronal responses, and the regulation of cell growth. Antagonists of this receptor have a potential therapeutic use in inhibiting tumor cell growth. Polymorphisms in this gene may be associated with a susceptibility for schizophrenia. Alternative splicing of this gene results in multiple transcript variants.
  • Alternative Names
  • BB1; BB1R; NMB-R; neuromedin-B receptor; bombesin receptor 1; epididymis secretory sperm binding protein Li 185a; epididymis tissue protein Li 185a; neuromedin-B-preferring bombesin receptor; NMBR; Neuromedin B receptor

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