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NativeExtract™ Human P2RY2 Membrane Protein (Full length, Super Nanodisc) (CAT#: S01YF-1023-KX82)

Datasheet
This product is recombinant Human P2RY2 protein in native nanodisc form. The synthetic compound we developed can solubilize the P2RY2 protein from membrane while retaining the native structure.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • P2RY2
  • Protein Length
  • Full length
  • Molecular Weight
  • 42.3kDa

Product Description

  • Activity
  • Yes
  • Application
  • ELISA; SPR Binding Assays; Phage Display Screening; Immunity; Functional Assays
  • Expression Systems
  • HEK293 expression system
  • Tag
  • Flag tag at the C-terminus
  • Protein Format
  • Native Nanodisc
  • Buffer
  • 20 mM Tris-HCl, 150 mM NaCl, pH 8.0

Target

  • Target Protein
  • P2RY2
  • Full Name
  • Purinergic receptor P2Y2
  • Introduction
  • The product of this gene belongs to the family of P2 receptors, which is activated by extracellular nucleotides and subdivided into P2X ligand-gated ion channels and P2Y G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor, found on many cell types, is activated by ATP and UTP and is reported to be overexpressed on some cancer cell types. It is involved in many cellular functions, such as proliferation, apoptosis and inflammation. Three transcript variants encoding the same protein have been identified for this gene.
  • Alternative Names
  • P2U; HP2U; P2U1; P2UR; P2Y2; P2RU1; P2Y2R; P2Y purinoceptor 2; ATP receptor; P2U nucleotide receptor; P2U purinoceptor 1; P2U receptor 1; purinergic receptor P2Y, G-protein coupled, 2; purinoceptor P2Y2; P2RY2; Purinergic receptor P2Y2

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