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NativeExtract™ Human S1PR5 Membrane Protein (Full length, Super Nanodisc) (CAT#: S01YF-1023-KX49)

Datasheet
This product is recombinant Human S1PR5 protein in native nanodisc form. The synthetic compound we developed can solubilize the S1PR5 protein from membrane while retaining the native structure.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • S1PR5
  • Protein Length
  • Full length
  • Molecular Weight
  • 41.8kDa

Product Description

  • Activity
  • Yes
  • Application
  • ELISA; SPR Binding Assays; Phage Display Screening; Immunity; Functional Assays
  • Expression Systems
  • HEK293 expression system
  • Tag
  • Flag tag at the C-terminus
  • Protein Format
  • Native Nanodisc
  • Buffer
  • 20 mM Tris-HCl, 150 mM NaCl, pH 8.0

Target

  • Target Protein
  • S1PR5
  • Full Name
  • Sphingosine-1-phosphate receptor 5
  • Introduction
  • The lysosphingolipid sphingosine 1-phosphate (S1P) regulates cell proliferation, apoptosis, motility, and neurite retraction. Its actions may be both intracellular as a second messenger and extracellular as a receptor ligand. S1P and the structurally related lysolipid mediator lysophosphatidic acid (LPA) signal cells through a set of G protein-coupled receptors known as EDG receptors. Some EDG receptors (e.g., EDG1; MIM 601974) are S1P receptors; others (e.g., EDG2; MIM 602282) are LPA receptors.
  • Alternative Names
  • EDG8; S1P5; Edg-8; SPPR-1; SPPR-2; S1P receptor 5; S1P receptor Edg-8; endothelial differentiation G-protein-coupled receptor 8; endothelial differentiation, sphingolipid G-protein-coupled receptor, 8; sphingosine 1-phosphate receptor EDG8; sphingosine 1-phosphate receptor Edg-8; S1PR5; Sphingosine-1-phosphate receptor 5

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