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NativeExtract™ Human TAS2R38 Membrane Protein (Full length, Super Nanodisc) (CAT#: S01YF-1023-KX40)

Datasheet
This product is recombinant Human TAS2R38 protein in native nanodisc form. The synthetic compound we developed can solubilize the TAS2R38 protein from membrane while retaining the native structure.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • TAS2R38
  • Protein Length
  • Full length
  • Molecular Weight
  • 37.9kDa

Product Description

  • Activity
  • Yes
  • Application
  • ELISA; SPR Binding Assays; Phage Display Screening; Immunity; Functional Assays
  • Expression Systems
  • HEK293 expression system
  • Tag
  • Flag tag at the C-terminus
  • Protein Format
  • Native Nanodisc
  • Buffer
  • 20 mM Tris-HCl, 150 mM NaCl, pH 8.0

Target

  • Target Protein
  • TAS2R38
  • Full Name
  • Taste 2 receptor member 38
  • Introduction
  • This gene encodes a seven-transmembrane G protein-coupled receptor that controls the ability to taste glucosinolates, a family of bitter-tasting compounds found in plants of the Brassica sp. Synthetic compounds phenylthiocarbamide (PTC) and 6-n-propylthiouracil (PROP) have been identified as ligands for this receptor and have been used to test the genetic diversity of this gene. Although several allelic forms of this gene have been identified worldwide, there are two predominant common forms (taster and non-taster) found outside of Africa. These alleles differ at three nucleotide positions resulting in amino acid changes in the protein (A49P, A262V, and V296I) with the amino acid combination PAV identifying the taster variant (and AVI identifying the non-taster variant).
  • Alternative Names
  • PTC; T2R38; T2R61; THIOT; taste receptor type 2 member 38; PTC bitter taste receptor; taste receptor type 2 member 61; taste receptor, type 2, member 38; TAS2R38; Taste 2 receptor member 38

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