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MemDX™ Recombinant Full Length Human AQP3 Protein (Biotinylated Nanodisc, Rho1D4 Tag) (CAT#: SYF-0926-CW51)

Recombinant full-length human AQP3 protein reconstituted in a biotinylated nanodisc membrane-mimetic system for immobilization, binding, detection, and assay development applications; the copolymer is biotinylated while the protein itself remains unmodified.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • AQP3
  • Protein Length
  • Full-length
  • Protein Class
  • Aquaporin
  • Molecular Weight
  • 32 kDa (homotetramer)
  • Sequence
  • MGRQKELVSRCGEMLHIRYRLLRQALAECLGTLILVMFGCGSVAQVVLSRGTHGGFLTINLAFGFAVTLGILIAGQVSGAHLNPAVTFAMCFLAREPWIKLPIYTLAQTLGAFLGAGIVFGLYYDAIWHFADNQLFVSGPNGTAGIFATYPSGHLDMINGFFDQFIGTASLIVCVLAIVDPYNNPVPRGLEAFTVGLVVLVIGTSMGFNSGYAVNPARDFGPRLFTALAGWGSAVFTTGQHWWWVPIVSPLLGSIAGVFVYQLMIGCHLEQPPPSNEEENVKLAHVKHKEQI

Product Description

  • Expression Systems
  • HEK293 cells
  • Tag
  • The construct includes a C-terminal Rho1D4 tag. The copolymer is biotinylated; the protein itself is unmodified.
  • Protein Format
  • Nanodisc
  • Purity
  • The protein purity is greater than 90% as determined by SDS-PAGE.

Target

  • Target Protein
  • AQP3
  • Full Name
  • aquaporin 3
  • Introduction
  • Aquaglyceroporin-3 (AQP3) is a full-length human aquaporin. Aquaporin-3 is a homotetrameric channel in which each monomer independently mediates the transport of glycerol and water along its osmotic gradient. In humans, it functions mainly in the kidney, where it plays a crucial role in the reabsorption of water, leading to the maintenance of fluid balance, and in the skin, where it is involved in the transport of glycerol, which is relevant for elasticity and hydration. The surrounding nanodisc copolymer is biotinylated to support direct surface immobilization without modifying the protein itself. The preparation uses 2-step purification.
  • Alternative Names
  • GIL

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