Close
Online Inquiry
CONTACT US
:
:
:
Call us at:
:
:
:
Fax:
Email:

MemDX™ Recombinant Full Length Human ITGAV/ITGB3 Protein (Nanodisc, Rho1D4 Tag & Strep Tag) (CAT#: SYF-0926-CW131)

Recombinant full-length human ITGAV; ITGB3 protein reconstituted in a nanodisc membrane-mimetic system for biochemical, binding, and assay development applications.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • ITGAV; ITGB3
  • Protein Length
  • Full-length
  • Protein Class
  • Integrin
  • Molecular Weight
  • ITGAV: 117 kDa; ITGB3: 88 kDa

Product Description

  • Expression Systems
  • HEK293 cells (co-expression)
  • Tag
  • The ITGAV subunit includes a C-terminal Strep tag, and the ITGB3 subunit includes a C-terminal Rho1D4 tag.
  • Protein Format
  • Nanodisc
  • Purity
  • The protein purity is greater than 90% as determined by SDS-PAGE.

Target

  • Target Protein
  • ITGAV; ITGB3
  • Full Name
  • ITGAV: integrin subunit alpha V; ITGB3: integrin subunit beta 3
  • Introduction
  • Integrin alpha-V / Integrin beta-3 complex (ITGAV/ITGB3) is a full-length human integrin. The heterodimer of ITGB3 and ITGAV, forming the αVβ3 integrin, is associated with various diseases, including cancer, cardiovascular conditions (like atherosclerosis and restenosis), bone diseases (such as osteoporosis), ocular disorders (age-related macular degeneration and diabetic retinopathy), fibrosis, and thrombosis-related bleeding disorders like Glanzmann thrombasthenia. Additionally, it plays a role in autoimmune diseases like multiple sclerosis and rheumatoid arthritis. The protein is supplied in an MSP-free, copolymer-stabilized native-lipid nanodisc. The preparation uses 3-step purification.
  • Alternative Names
  • ITGAV: CD51, VNRA, MSK8, VTNR; ITGB3: CD61, GPIIIa, GP3A

Case Studies

Customer reviews and Q&As    

Related Products
Our customer service representatives are available 24 hours a day, 7 days a week. Contact Us
© 2026 Creative Biolabs. | Contact Us