Creative Biolabs is offering the most comprehensive services for antibody development projects. With strict regulation and effective execution, we are dedicated to providing the most valuable solutions to complete your projects.
Creative Biolabs is offering the most comprehensive services for antibody development projects. With strict regulation and effective execution, we are dedicated to providing the most valuable solutions to complete your projects.
Creative Biolabs is offering the most comprehensive services for antibody development projects. With strict regulation and effective execution, we are dedicated to providing the most valuable solutions to complete your projects.
Creative Biolabs is offering the most comprehensive services for antibody development projects. With strict regulation and effective execution, we are dedicated to providing the most valuable solutions to complete your projects.
With over a decade of experience in phage display technology, Creative Biolabs can provide a series of antibody or peptide libraries that are available for licensing or direct screening. These ready-to-use libraries are invaluable resources for isolating target-specific binders for various research, diagnostic or therapeutic applications.
Creative Biolabs has established a broad range of platforms for developing novel antibodies or equivalents. These cutting-edge technologies enable our scientists to meet your demands from different aspects and tailor the most appropriate solution that contributes to the success of your projects.
With deep understanding in antibody-related realms and extensive project experience, Creative Biolabs offers a variety of references to help you learn more about our capacities and achievements, including infographic, flyer, case study, peer-reviewed publications, and all kinds of knowledge that can assist your projects. You are also welcome to contact us directly for more specific solutions.
Get a real taste of Creative Biolabs, one of the most professional custom service providers in the world. We are committed to providing highly customized comprehensive solutions with the best quality to advance your projects.
Recombinant full-length human ITGAV; ITGB3 protein reconstituted in a nanodisc membrane-mimetic system for biochemical, binding, and assay development applications.
Product Specifications
Host Species
Human
Target Protein
ITGAV; ITGB3
Protein Length
Full-length
Protein Class
Integrin
Molecular Weight
ITGAV: 117 kDa; ITGB3: 88 kDa
Product Description
Expression Systems
HEK293 cells (co-expression)
Tag
The ITGAV subunit includes a C-terminal Strep tag, and the ITGB3 subunit includes a C-terminal Rho1D4 tag.
Protein Format
Nanodisc
Purity
The protein purity is greater than 90% as determined by SDS-PAGE.
Integrin alpha-V / Integrin beta-3 complex (ITGAV/ITGB3) is a full-length human integrin. The heterodimer of ITGB3 and ITGAV, forming the αVβ3 integrin, is associated with various diseases, including cancer, cardiovascular conditions (like atherosclerosis and restenosis), bone diseases (such as osteoporosis), ocular disorders (age-related macular degeneration and diabetic retinopathy), fibrosis, and thrombosis-related bleeding disorders like Glanzmann thrombasthenia. Additionally, it plays a role in autoimmune diseases like multiple sclerosis and rheumatoid arthritis. The protein is supplied in an MSP-free, copolymer-stabilized native-lipid nanodisc. The preparation uses 3-step purification.