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- Antigen Species: Human
- Type: Membrane Protein
- Expression System: HEK293
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Datasheet
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- Target Classification: Ion Channel
- Target Protein: CFTR
- Target Protein Species: Human
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Datasheet
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- Target Classification: Ion Channel
- Target Protein: CFTR
- Target Protein Species: Human
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Datasheet
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- Classification: PEGylation, Lipids (PEG-PE)
- Purity: >95%
- Storage: -20°C
- Shelf Time: 1 year
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Datasheet
All listed services and products are For Research Use Only. Do Not use in any diagnostic or therapeutic applications.
An ATP-binding cassette (ABC) transporter superfamily member is encoded by this gene. The encoded protein regulates ion and water secretion and absorption in epithelial tissues and, unlike other members of this protein family, acts as a chloride channel. The cycles of ATP binding by the nucleotide-binding domains, regulatory domain phosphorylation, and ATP hydrolysis are what cause channel activation. Cystic fibrosis, the most prevalent deadly genetic illness among people of Northern European origin, is brought on by mutations in this gene.