Creative Biolabs is offering the most comprehensive services for antibody development projects. With strict regulation and effective execution, we are dedicated to providing the most valuable solutions to complete your projects.
HighlightsCreative Biolabs is offering the most comprehensive services for antibody development projects. With strict regulation and effective execution, we are dedicated to providing the most valuable solutions to complete your projects.
HighlightsCreative Biolabs has established a broad range of platforms for developing novel antibodies or equivalents. These cutting-edge technologies enable our scientists to meet your demands from different aspects and tailor the most appropriate solution that contributes to the success of your projects.
HighlightsWith deep understanding in antibody-related realms and extensive project experience, Creative Biolabs offers a variety of references to help you learn more about our capacities and achievements, including infographic, flyer, case study, peer-reviewed publications, and all kinds of knowledge that can assist your projects. You are also welcome to contact us directly for more specific solutions.
HighlightsGet a real taste of Creative Biolabs, one of the most professional custom service providers in the world. We are committed to providing highly customized comprehensive solutions with the best quality to advance your projects.
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Loading...All listed services and products are For Research Use Only. Do Not use in any diagnostic or therapeutic applications.
Interferon alpha inducible protein 27 (IFI27, also known as ISG12A) is a small hydrophobic interferon-stimulated protein encoded by the IFI27 gene and associated primarily with intracellular membrane compartments, including mitochondria. Distinct from cell-surface receptors, IFI27 lacks a characterized extracellular ligand-binding ectodomain and does not function as a plasma-membrane receptor. It is strongly induced by type I interferon and has been studied as an intracellular membrane-associated effector in interferon-responsive cells. Reported functions are context dependent and include effects on mitochondrial stress and apoptosis-related responses in some model systems. Other studies have linked IFI27 to antiviral responses through intracellular mechanisms, without establishing a general cell-surface signaling role. Accordingly, IFI27 research is better centered on interferon-induced expression, intracellular localization, and associated stress or antiviral phenotypes.
Variants of the IFI27 gene may alter protein expression or intracellular function and correlate with changes in interferon-responsive cellular phenotypes. Shifts in IFI27 expression levels commonly align with cellular interferon-exposure status, rendering it a suitable research subject for interferon-inducible membrane-associated protein and cellular response analysis. IFI27 has been reported at mitochondrial and other intracellular membrane compartments, and its subcellular distribution can vary with experimental context; these observations do not support a defined extracellular partner-binding or plasma-membrane signal-transduction mechanism. Altered IFI27 expression may influence intracellular stress, apoptosis-related, or antiviral phenotypes, supporting its value for basic interferon-response studies.
Fig. 1 Gene structure diagram of IFI27, illustrating UTR regions, exons, introns and the ATG translation initiation site.1
The biological functions of IFI27 are context dependent and are studied mainly in relation to interferon-induced expression, intracellular membrane association, and downstream cellular responses:
Creative Biolabs offers purified IFI27 protein samples produced under unified preparation workflows, including full-length IFI27 constructs and selected sequence variants. Full-length constructs suit research focused on interferon-induced protein behavior, intracellular membrane association, and related biochemical studies. All batches receive uniform quality screening. Functional observation should be designed according to the intended assay and relevant intracellular membrane context. Consistent structural features are preserved across batches to support comparative laboratory analysis across separate test groups. Full-length IFI27 samples can support comparative studies of IFI27-related intracellular membrane processes without implying extracellular ligand-binding activity.
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Creative Biolabs provides adjustable IFI27 expression cell research models with varied expression levels, applicable to studies of interferon-inducible membrane-associated proteins and intracellular localization or response phenotypes. Sample evaluation includes sustained target expression detection and preliminary intracellular localization or phenotype observation, enabling side-by-side comparison under differing expression abundances. These cell systems can pair with diverse laboratory analysis schemes to track expression-associated changes in cellular responses.
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Anti-IFI27 recombinant antibodies are generated via standardized protein preparation workflows, compatible with routine laboratory detection techniques for intracellular localization mapping and analysis of IFI27 expression. The antibody series can work alongside common laboratory detection reagents to support observation of target distribution within cellular or tissue samples.
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Beyond catalog products, Creative Biolabs offers specialized custom services for IFI27 research:
IFI27 is an interferon-inducible, membrane-associated intracellular protein that has been linked to mitochondrial stress, apoptosis-related responses, and antiviral activity in a context-dependent manner.
IFI27 expression is strongly responsive to interferon and has been associated with intracellular stress and antiviral phenotypes, making it useful for studying interferon-induced cellular responses.
No, all IFI27 related products and services are strictly for research use only, and cannot be applied in clinical workflows. All material designs and functional tests are optimized exclusively for basic laboratory research scenarios, without matching clinical application standards.
Offerings include full-length IFI27 membrane protein, target-specific recombinant antibodies and tunable expression cell research models, supporting research on intracellular localization and interferon-responsive cellular processes.
Laboratory observation schemes may include expression analysis, intracellular localization assays, and context-appropriate functional readouts under relevant cellular conditions.
