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KCNQ2

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The potassium channel M, which slowly activates and deactivates, is essential for controlling the excitability of neurons. The protein produced by this gene and a similar protein expressed by the KCNQ3 gene, both of which are essential membrane proteins, come together to create the M channel. M1 muscarinic acetylcholine receptors inhibit M channel currents, while retigabine, a novel anti-convulsant medication, activates them. Benign neonatal type 1 epilepsy, also known as benign familial neonatal convulsions type 1, is brought on by errors in this gene.
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