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- Antigen Species: Human
- Type: Membrane Protein
- Expression System: HEK293
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Datasheet
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- Antigen Species: Human
- Type: Membrane Protein
- Expression System: in vitro wheat germ expression system
- Application: Enzyme-linked Immunoabsorbent Assay, Western Blot (Recombinant protein), Antibody Production, Protein Array
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Datasheet
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- Target Classification: Ion Channel
- Target Protein: KCNQ2/KCNQ4
- Target Protein Species: Human
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Datasheet
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- Target Classification: Ion Channel
- Target Protein: KCNQ2/KCNQ3
- Target Protein Species: Human
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Datasheet
All listed services and products are For Research Use Only. Do Not use in any diagnostic or therapeutic applications.
The potassium channel M, which slowly activates and deactivates, is essential for controlling the excitability of neurons. The protein produced by this gene and a similar protein expressed by the KCNQ3 gene, both of which are essential membrane proteins, come together to create the M channel. M1 muscarinic acetylcholine receptors inhibit M channel currents, while retigabine, a novel anti-convulsant medication, activates them. Benign neonatal type 1 epilepsy, also known as benign familial neonatal convulsions type 1, is brought on by errors in this gene.