Creative Biolabs is offering the most comprehensive services for antibody development projects. With strict regulation and effective execution, we are dedicated to providing the most valuable solutions to complete your projects.
HighlightsCreative Biolabs is offering the most comprehensive services for antibody development projects. With strict regulation and effective execution, we are dedicated to providing the most valuable solutions to complete your projects.
HighlightsCreative Biolabs has established a broad range of platforms for developing novel antibodies or equivalents. These cutting-edge technologies enable our scientists to meet your demands from different aspects and tailor the most appropriate solution that contributes to the success of your projects.
HighlightsWith deep understanding in antibody-related realms and extensive project experience, Creative Biolabs offers a variety of references to help you learn more about our capacities and achievements, including infographic, flyer, case study, peer-reviewed publications, and all kinds of knowledge that can assist your projects. You are also welcome to contact us directly for more specific solutions.
HighlightsGet a real taste of Creative Biolabs, one of the most professional custom service providers in the world. We are committed to providing highly customized comprehensive solutions with the best quality to advance your projects.
Highlights
Loading...All listed services and products are For Research Use Only. Do Not use in any diagnostic or therapeutic applications.
The MYADM gene is located in the region of human chromosome 19q13.42 and encodes the MYADM protein, a myeloid-related differentiation marker. This protein belongs to the transmembrane protein family with MARVEL domains. The MYADM protein consists of approximately 180 amino acids and has a molecular weight of about 20 kDa. It is mainly expressed in hematopoietic stem cells, myeloid cells, and various epithelial tissues, and is located on the cell membrane and participates in processes such as cell adhesion, membrane microdomain organization, and tight junction regulation. As an important regulator of cell membrane structure, MYADM plays a potential role in myeloid differentiation and inflammatory-related signal transduction. This gene has multiple single nucleotide polymorphism loci. Some missense variations may affect the membrane localization or oligomerization ability of the protein, thereby altering cell-cell interactions and immune response efficiency. In addition, abnormal expression levels of MYADM are associated with certain hematological diseases and the progression of solid tumors. Therefore, MYADM is regarded as a candidate gene in the study of cell differentiation regulation and disease biomarkers, and its variant analysis provides valuable molecular tools for exploring the functional mechanism of membrane proteins and pathological processes related to individual differences.
Fig. 1 Schematic representation of the human MYADM protein structure.1
The functional spectrum of MYADM protein is quite extensive, and the related understanding is still continuously deepening:
Creative Biolabs offers a series of high-quality MYADM membrane protein products, which are suitable for structural analysis and functional research. Relying on the independently developed MemDX™ recombinant membrane protein technology platform, MYADM proteins can be produced in various expression systems, including virus-like particles (VLP) form and in vitro prokaryotic expression systems. These rigorously validated protein products, such as MemDX™ recombinant human MYADM membrane protein (in VLP form) and different tag-selected full-length MYADM membrane proteins, can be used in applications such as ELISA, antibody development and identification, binding experiments, and functional analysis. These products provide reliable tool support for researchers to analyze the interaction network and membrane-related activity mechanisms of MYADM.
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Constructing reliable cell models is an important foundation for conducting functional studies on MYADM membrane proteins. As a molecule involved in myeloid differentiation and membrane microdomain regulation, the biological function of MYADM is closely related to its localization and organization within cellular membranes. Its cellular behavior may vary depending on the expression context and experimental conditions. Creative Biolabs offers customized MYADM stable expression cell models for studies of MYADM expression and localization. These models can stably express the target protein and are suitable for applications such as protein-protein interaction analysis, membrane localization detection, membrane microdomain organization studies, and related functional investigations, providing a reliable and reproducible experimental platform for exploring the molecular function, structure-function relationship, and role of MYADM in membrane organization. Our technology supports stable target expression and appropriate cellular localization, facilitating further research on MYADM biology.
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Creative Biolabs offers highly specific recombinant antibodies targeting the MYADM protein, produced using advanced genetic engineering recombinant antibody technology. Compared to traditional polyclonal antibodies, these recombinant antibodies demonstrate significant advantages in terms of specificity, sensitivity, and batch-to-batch consistency. Our MYADM recombinant antibodies support various application scenarios, including Western Blot (WB), Enzyme-Linked Immunosorbent Assay (ELISA), Flow Cytometry (FCM), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (IHC), and Immunoprecipitation (IP), and can be used to detect differences in the expression levels of different MYADM variants, analyze their localization and distribution in tissues or cells, and study the interaction relationships between proteins. These antibodies provide reliable detection tools for the structural analysis, functional exploration, and polymorphism analysis of MYADM.
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In addition to the listed products, Creative Biolabs also offers customized special services for MYADM. The MYADM protein has multiple naturally occurring variants with significantly different functions, and it poses specific requirements for protein expression strategies, antigen design, and functional validation. Leveraging our technology platform, we can assist you in the following tasks:
MYADM mainly participates in the organization and stability of the cell membrane microdomain, and plays a regulatory role in myeloid differentiation and inflammatory-related signal transduction. The function of this protein is influenced by its natural genetic variations. Different variants may have differences in membrane localization ability or oligomerization state, and it is an important model for studying the relationship between the structure and function of membrane proteins.
MYADM has multiple natural genetic variations, which may lead to changes in protein membrane localization or alterations in the ability of cells to interact with each other. Studying the polymorphisms of MYADM is helpful for understanding the relationship between the structure and function of membrane proteins, the molecular mechanisms of cell differentiation regulation, and the influencing factors of membrane organization stability.
No. All MYADM products and services provided by Creative Biolabs are strictly for research purposes only and cannot be used for clinical diagnosis, prevention, treatment or cure of any disease.
We provide a variety of product types, including recombinant MYADM membrane proteins, stable cell models expressing MYADM, high-quality recombinant MYADM antibodies, and comprehensive customized services.
