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SSTR5

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All listed services and products are For Research Use Only. Do Not use in any diagnostic or therapeutic applications.

By interacting with somatostatin receptors, somatostatin and the related peptide cortistatin have a variety of biological effects on both normal and tumoral tissue targets. One of the SSTRs, a multi-pass membrane protein that is a member of the G-protein coupled receptor 1 family, is the protein that is produced by this gene. Different sections of this receptor molecule are necessary for the activation of various signaling pathways. This receptor's action is mediated by G proteins that block adenylyl cyclase. Somatostatin analog resistance is brought on by a mutation in this gene.
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