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TNFRSF17

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This gene encodes a protein that belongs to the TNF-receptor superfamily. This receptor is mostly expressed in mature B lymphocytes and may have a role in the formation of B cells and the immune system's response. It has been demonstrated that this receptor specifically binds to TNFSF13B/TALL-1, a member of the tumor necrosis factor (ligand) superfamily, activating NF-kappaB and MAPK8/JNK. This receptor can transmit signals for cell survival and growth by binding to different TRAF family members.
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