Creative Biolabs is offering the most comprehensive services for antibody development projects. With strict regulation and effective execution, we are dedicated to providing the most valuable solutions to complete your projects.
HighlightsCreative Biolabs is offering the most comprehensive services for antibody development projects. With strict regulation and effective execution, we are dedicated to providing the most valuable solutions to complete your projects.
HighlightsCreative Biolabs has established a broad range of platforms for developing novel antibodies or equivalents. These cutting-edge technologies enable our scientists to meet your demands from different aspects and tailor the most appropriate solution that contributes to the success of your projects.
HighlightsWith deep understanding in antibody-related realms and extensive project experience, Creative Biolabs offers a variety of references to help you learn more about our capacities and achievements, including infographic, flyer, case study, peer-reviewed publications, and all kinds of knowledge that can assist your projects. You are also welcome to contact us directly for more specific solutions.
HighlightsGet a real taste of Creative Biolabs, one of the most professional custom service providers in the world. We are committed to providing highly customized comprehensive solutions with the best quality to advance your projects.
Highlights| Protein Name | Cysteinyl leukotriene receptor 2 |
| Gene Name | CYSLTR2 |
| Uniprot | Q9NS75 (Human); Q920A1 (Mouse) |
| Synonym | HG57; CYSLT2; GPCR21; HPN321; CYSLT2R; KPG_011; hGPCR21; PSEC0146; G-protein coupled receptor GPCR21; G-protein coupled receptor HG57; cysteinyl leukotriene CysLT2 receptor |
| Background | CysLTR2 is encoded by the CysLTR2 gene and is a receptor for cysteinyl leukotrienes. It belongs to the G-protein-coupled receptor (GPCR) family which has been extensively studied during the past few decades because it offers numerous possibilities for therapeutic applications. The cysteinyl leukotrienes LTC4, LTD4, and LTE4 are important mediators of human bronchial asthma. Pharmacologic studies have determined that cysteinyl leukotrienes activate at least 2 receptors, the protein encoded by this gene and CYSLTR1. It seems to play a major role in endocrine and cardiovascular systems. |
Creative Biolabs offers comprehensive range of membrane protein products empowers your unique research needs.
| CAT# | Product Name | Expression System | Protein Length | Solubilizing Agents |
| S01YF-1023-KX288 | NativeExtract™ Human CYSLTR2 Membrane Protein (Full length, Super Nanodisc) | HEK293 cells | Full length | Native Nanodisc |
| MPX3400K | MemDX™ Membrane Protein Human CYSLTR2 Expressed in vitro E.coli expression system, Full Length | E.coli cell-free | Full length | Detergent |
| Please for more products or customization | ||||
M**y: I recently purchased the protein from Creative Biolabs. It has been a crucial component in my research, and I am very satisfied with the results.
03/May/2023
H***y: The shipping was fast, and the packaging ensured that the protein arrived in perfect condition. I am very impressed with the overall experience and would highly recommend Creative Biolabs to anyone.
22/Jan/2024
We provide tailored solutions to meet your specific requirements. Please for more services.
Gene Editing
Creative Biolabs offers gene editing services. Sophisticated genome engineering methodologies offer unparalleled capabilities for targeted molecular manipulation within specific cellular populations. These advanced approaches permit the precise modulation of genomic loci, thereby enabling a spectrum of intricate genetic alterations. This capacity for direct genetic intervention consequently offers the potential for significant therapeutic advancements. For instance, in pathological conditions such as uveal melanoma, the targeted modification of CYSLTR2 may conceivably ameliorate disease progression or restore physiological function, thus opening new avenues for clinical intervention.
Gene Delivery
Creative Biolabs offers gene delivery services. Recombinant viral vectors, encompassing notably adenoviral and lentiviral platforms, are extensively employed as sophisticated gene delivery systems. These vehicles are meticulously engineered to facilitate the intracellular transduction of therapeutic genetic constructs, which are specifically designed to modulate the expression or integrity of the CYSLTR2 gene. For instance, such vectors can be precisely customized to effectuate the transcriptional synthesis of short hairpin RNA (shRNA) molecules or guide RNA (gRNA) sequences. The strategic deployment of these RNA species enables the precise attenuation of CYSLTR2 gene expression or the introduction of targeted genomic modifications at the CYSLTR2 locus, respectively, thereby offering versatile tools for experimental manipulation and potential therapeutic intervention.
Creative Biolabs offers comprehensive and innovative services to drive the development of CYSLTR2 cell therapy. Please for more services.
Endothelial Permeability Assay
Creative Biolabs offers endothelial permeability assay services. An established in vitro analytical methodology offers a precise means to systematically investigate the functional influence of CYSLTR2 upon endothelial barrier integrity, specifically its impact on paracellular permeability. This experimental paradigm provides critical insights into the mechanistic underpinnings of vascular regulation.
Tumor Models
Creative Biolabs offers tumor model development services. H Preclinical animal models, notably syngeneic tumor systems, constitute indispensable experimental paradigms for oncology research. These platforms enable the meticulous investigation into the precise mechanistic contribution of specific molecular entities within the intricate processes of neoplastic advancement and subsequent metastatic dissemination. Following the orthotopic or subcutaneous implantation of tumor cells into immunocompetent recipient murine hosts, the experimental system is established. Subsequently, the systemic or localized consequences of either CYSLTR2 agonist-mediated activation or antagonist-induced inhibition upon primary tumor proliferation and secondary site colonization can be rigorously evaluated.
Bioinformatics Analysis
Creative Biolabs offers bioinformatics analysis services. The wealth of information enables the systematic interrogation of the transcriptional profiles and genomic alterations of specific molecular entities across a heterogeneous spectrum of diverse clinical pathologies. Such comprehensive bioinformatic analyses of high-throughput data can consequently facilitate crucial advancements in translational research. These endeavors inherently assist in the discernment of novel molecular targets for therapeutic intervention. Furthermore, they prove instrumental in the identification of putative prognostic or diagnostic biomarkers, thereby potentially refining disease stratification and guiding personalized treatment strategies.
All listed services and products are For Research Use Only. Do Not use in any diagnostic or therapeutic applications.
